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UniProtKB/Swiss-Prot entry Q73QV3


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ALF1_TREDE
Primary accession number Q73QV3
Secondary accession numbers None
Integrated into Swiss-Prot on March 1, 2005
Sequence was last modified on July 5, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 30)
Name and origin of the protein
Protein name Fructose-bisphosphate aldolase class 1
Synonyms EC 4.1.2.13
Fructose-biphosphate aldolase class I
FBP aldolase
Gene name
Name: fda
OrderedLocusNames: TDE_0340
From
Treponema denticola [TaxID: 158] [HAMAP proteome]
Taxonomy Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Treponema.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 35405 / CIP 103919 / DSM 14222;
DOI=10.1073/pnas.0307639101; PubMed=15064399 [NCBI, ExPASy, EBI, Israel, Japan]
Seshadri R., Myers G.S.A., Tettelin H., Eisen J.A., Heidelberg J.F., Dodson R.J., Davidsen T.M., DeBoy R.T., Fouts D.E., Haft D.H., Selengut J., Ren Q., Brinkac L.M., Madupu R., Kolonay J.F., Durkin S.A., Daugherty S.C., Shetty J., Shvartsbeyn A., Gebregeorgis E., Geer K., Tsegaye G., Malek J.A., Ayodeji B., Shatsman S., McLeod M.P., Smajs D., Howell J.K., Pal S., Amin A., Vashisth P., McNeill T.Z., Xiang Q., Sodergren E., Baca E., Weinstock G.M., Norris S.J., Fraser C.M., Paulsen I.T.;
"Comparison of the genome of the oral pathogen Treponema denticola with other spirochete genomes.";
Proc. Natl. Acad. Sci. U.S.A. 101:5646-5651(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE017226; AAS10835.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_970954.1; -.
3D structure databases
ModBase Q73QV3.
Enzyme and pathway databases
BioCyc TDEN243275:TDE_0340-MON; -.
Ontologies
GO
GO:0004332; Molecular function: fructose-bisphosphate aldolase activity (inferred from electronic annotation from HAMAP).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00729; -; 1.
PBIL [Tree]
InterPro IPR000741; Aldolase_I.
IPR013785; Aldolase_TIM.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF00274; Glycolytic; 1.
Pfam graphical view of domain structure.
ProDom PD001128; Aldolase_I; 1.
[Domain structure / List of seq. sharing at least 1 domain]
PROSITE PS00158; ALDOLASE_CLASS_I; FALSE_NEG.
Genome annotation databases
GeneID 2739339; -.
GenomeReviews AE017226_GR; TDE_0340.
KEGG tde:TDE0340; -.
NMPDR fig|243275.1.peg.337; -.
TIGR TDE_0340; -.
Phylogenomic databases
HOGENOM Q73QV3; -.
Other
ProtoNet Q73QV3.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Glycolysis; Lyase; Schiff base.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   295  295     Fructose-bisphosphate aldolase class 1. PRO_0000216914
ACT_SITE   176   176        Proton acceptor (By similarity). 
ACT_SITE   213   213        Schiff-base intermediate with dihydroxyacetone-P (By similarity). 
Sequence information
Length: 295 AA [This is the length of the unprocessed precursor] Molecular weight: 32805 Da [This is the MW of the unprocessed precursor] CRC64: 5C1A6403A7D4EA20 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MDKVKLERMK NDKGFIAALD QSGGSTPKAL AAYGVPETAY SNEKEMFDLV HAMRTRIITG 

        70         80         90        100        110        120 
KAFNSNNILG AILFEQTMER EIEGMPTADF LWEKKKILPF LKVDKGLADL KDGVQLMKPI 

       130        140        150        160        170        180 
PNLDAMLKHA VEKHIFGTKM RSVIKEANPK GIKAVVDQQF ELGIQIAKAG LVPIIEPEVD 

       190        200        210        220        230        240 
IKSPDKAKCE EILKKELEEH LKTLPKDLLV MFKLSIPTKE NLYEEFTKHP QVVRVVALSG 

       250        260        270        280        290 
GYSRDDANKL LAKNRGMIAS FSRALAEGLF ASQSDAEFNA TLEKTIKGVY EASIT 

Q73QV3 in FASTA format

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