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UniProtKB/Swiss-Prot entry Q7A4D8


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ALD1_STAAN
Primary accession number Q7A4D8
Secondary accession numbers None
Integrated into Swiss-Prot on July 10, 2007
Sequence was last modified on July 5, 2004 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 28)
Name and origin of the protein
Protein name Putative aldehyde dehydrogenase SA1924
Synonym EC 1.2.1.3
Gene name
OrderedLocusNames: SA1924
From
Staphylococcus aureus (strain N315) [TaxID: 158879] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Staphylococcus.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1016/S0140-6736(00)04403-2; PubMed=11418146 [NCBI, ExPASy, EBI, Israel, Japan]
Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L., Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M., Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y., Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H., Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K., Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H., Hiramatsu K.;
"Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
Lancet 357:1225-1240(2001).
[2]
IDENTIFICATION BY MASS SPECTROMETRY.
DOI=10.1016/j.mimet.2004.09.017; PubMed=15590099 [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A., Francois P., Bento M., Deshusses J.M., Charbonnier Y., Converset V., Huyghe A., Walter N., Hoogland C., Appel R.D., Sanchez J.-C., Zimmermann-Ivol C.G., Corthals G.L., Hochstrasser D.F., Schrenzel J.;
"Correlation of proteomic and transcriptomic profiles of Staphylococcus aureus during the post-exponential phase of growth.";
J. Microbiol. Methods 60:247-257(2005).
[3]
IDENTIFICATION BY MASS SPECTROMETRY.
Vaezzadeh A.R., Deshusses J., Lescuye P., Hochstrasser D.F.;
"Shotgun proteomic analysis of total and membrane protein extracts of S. aureus strain N315.";
Submitted (OCT-2007) to UniProtKB.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000018; BAB43208.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR G90005; G90005.
RefSeq NP_375229.1; -.
3D structure databases
HSSP P20000; 1AG8. [HSSP ENTRY / PDB]
ModBase Q7A4D8.
Enzyme and pathway databases
BioCyc SAUR158879:SA1924-MON; -.
2D gel databases
SWISS-2DPAGE Q7A4D8; -.
Family and domain databases
InterPro IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11699; Aldehyde_dehyd; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.
BLOCKS Q7A4D8.
Genome annotation databases
GeneID 1124825; -.
GenomeReviews BA000018_GR; SA1924.
KEGG sau:SA1924; -.
Phylogenomic databases
HOGENOM Q7A4D8; -.
Genome annotation databases
CMR Q7A4D8; SA1924.
Other
ProtoNet Q7A4D8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   475  475     Putative aldehyde dehydrogenase SA1924. PRO_0000293558
NP_BIND   201   207  7     NAD (By similarity). 
ACT_SITE   245   245        By similarity. 
ACT_SITE   279   279        By similarity. 
Sequence information
Length: 475 AA [This is the length of the unprocessed precursor] Molecular weight: 51969 Da [This is the MW of the unprocessed precursor] CRC64: 03C66ED0B87BC09A [This is a checksum on the sequence]
        10         20         30         40         50         60 
MRDYTKQYIN GEWVESNSNE TIEVINPATE EVIGKVAKGN KADVDKAVEA ADDVYLEFRH 

        70         80         90        100        110        120 
TSVKERQALL DKIVKEYENR KDDIVQAITD ELGAPLSLSE RVHYQMGLNH FVAARDALDN 

       130        140        150        160        170        180 
YEFEERRGDD LVVKEAIGVS GLITPWNFPT NQTSLKLAAA FAAGSPVVLK PSEETPFAAV 

       190        200        210        220        230        240 
ILAEIFDKVG VPKGVFNLVN GDGAGVGNPL SEHPKVRMMS FTGSGPTGSK IMEKAAKDFK 

       250        260        270        280        290        300 
KVSLELGGKS PYIVLDDVDI KEAAKATTGK VVNNTGQVCT AGTRVLVPNK IKDAFLAELK 

       310        320        330        340        350        360 
EQFSQVRVGN PREDGTQVGP IISKKQFDQV QNYINKGIEE GAELFYGGPG KPEGLEKGYF 

       370        380        390        400        410        420 
ARPTIFINVD NQMTIAQEEI FGPVMSVITY NDLDEAIQIA NDTKYGLAGY VIGKDKETLH 

       430        440        450        460        470 
KVARSIEAGT VEINEAGRKP DLPFGGYKQS GLGREWGDYG IEEFLEVKSI AGYFK 

Q7A4D8 in FASTA format

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