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UniProtKB/Swiss-Prot entry Q7TYP6


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name SIR_MYCBO
Primary accession number Q7TYP6
Secondary accession numbers None
Integrated into Swiss-Prot on September 27, 2005
Sequence was last modified on September 27, 2005 (Sequence version 2)
Annotations were last modified on    July 22, 2008 (Entry version 28)
Name and origin of the protein
Protein name Sulfite reductase [ferredoxin]
Synonym EC 1.8.7.1
Gene name
Name: sir
Synonyms: nirA
OrderedLocusNames: Mb2412
From
Mycobacterium bovis [TaxID: 1765] [HAMAP proteome]
Taxonomy Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC BAA-935 / AF2122/97;
DOI=10.1073/pnas.1130426100; PubMed=12788972 [NCBI, ExPASy, EBI, Israel, Japan]
Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M., Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B., Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J., Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
"The complete genome sequence of Mycobacterium bovis.";
Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX248342; CAD97273.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_856061.1; -.
3D structure databases
ModBase Q7TYP6.
Ontologies
GO
GO:0050311; Molecular function: sulfite reductase (ferredoxin) activity (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR006066; Nir_Si_BS.
IPR006067; Nir_Sir_4Fe4S.
IPR005117; NiRdtase/SiRdtase_haem-b_fer.
Graphical view of domain structure.
Pfam PF01077; NIR_SIR; 2.
PF03460; NIR_SIR_ferr; 2.
Pfam graphical view of domain structure.
PRINTS PR00397; SIROHAEM.
PROSITE PS00365; NIR_SIR; 1.
BLOCKS Q7TYP6.
Genome annotation databases
GeneID 1094301; -.
GenomeReviews BX248333_GR; Mb2412.
KEGG mbo:Mb2412; -.
Phylogenomic databases
HOGENOM Q7TYP6; -.
Genome annotation databases
CMR Q7TYP6; Mb2412.
Other
ProtoNet Q7TYP6.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
4Fe-4S; Complete proteome; Heme; Iron; Iron-sulfur; Metal-binding; Oxidoreductase; Thioether bond.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   555  555     Sulfite reductase [ferredoxin]. PRO_0000199949
METAL   417   417        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   423   423        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   463   463        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   467   467        Iron (siroheme axial ligand) (By similarity). 
METAL   467   467        Iron-sulfur (4Fe-4S) (By similarity). 
CROSSLNK   69   161        3'-(S-cysteinyl)-tyrosine (Tyr-Cys) (By similarity). 
Sequence information
Length: 555 AA [This is the length of the unprocessed precursor] Molecular weight: 62112 Da [This is the MW of the unprocessed precursor] CRC64: 68925CA37C131BC3 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTTARPAKAR NEGQWALGHR EPLNANEELK KAGNPLDVRE RIENIYAKQG FDSIDKTDLR 

        70         80         90        100        110        120 
GRFRWWGLYT QREQGYDGTW TGDDNIDKLE AKYFMMRVRC DGGALSAAAL RTLGQISTEF 

       130        140        150        160        170        180 
ARDTADISDR QNVQYHWIEV ENVPEIWRRL DDVGLQTTEA CGDCPRVVLG SPLAGESLDE 

       190        200        210        220        230        240 
VLDPTWAIEE IVRRYIGKPD FADLPRKYKT AISGLQDVAH EINDVAFIGV NHPEHGPGLD 

       250        260        270        280        290        300 
LWVGGGLSTN PMLAQRVGAW VPLGEVPEVW AAVTSVFRDY GYRRLRAKAR LKFLIKDWGI 

       310        320        330        340        350        360 
AKFREVLETE YLKRPLIDGP APEPVKHPID HVGVQRLKNG LNAVGVAPIA GRVSGTILTA 

       370        380        390        400        410        420 
VADLMARAGS DRIRFTPYQK LVILDIPDAL LDDLIAGLDA LGLQSRPSHW RRNLMACSGI 

       430        440        450        460        470        480 
EFCKLSFAET RVRAQHLVPE LERRLEDINS QLDVPITVNI NGCPNSCARI QIADIGFKGQ 

       490        500        510        520        530        540 
MIDDGHGGSV EGFQVHLGGH LGLDAGFGRK LRQHKVTSDE LGDYIDRVVR NFVKHRSEGE 

       550 
RFAQWVIRAE EDDLR 

Q7TYP6 in FASTA format

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