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UniProtKB/Swiss-Prot entry Q7VUS1


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AROE_BORPE
Primary accession number Q7VUS1
Secondary accession numbers None
Integrated into Swiss-Prot on March 18, 2008
Sequence was last modified on October 1, 2003 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 36)
Name and origin of the protein
Protein name Shikimate dehydrogenase
Synonym EC 1.1.1.25
Gene name
Name: aroE
OrderedLocusNames: BP3004
From
Bordetella pertussis [TaxID: 520] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Alcaligenaceae; Bordetella.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Tohama I / ATCC BAA-589 / NCTC 13251;
DOI=10.1038/ng1227; PubMed=12910271 [NCBI, ExPASy, EBI, Israel, Japan]
Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J.;
"Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica.";
Nat. Genet. 35:32-40(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX640420; CAE43275.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_881579.1; -.
3D structure databases
HSSP P15770; 1NYT. [HSSP ENTRY / PDB]
ModBase Q7VUS1.
Enzyme and pathway databases
BioCyc BPER257313:BP3004-MON; -.
Ontologies
GO
GO:0004764; Molecular function: shikimate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0009073; Biological process: aromatic amino acid family biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00222; -; 1.
PBIL [Tree]
InterPro IPR016040; NAD(P)-bd.
IPR011342; Quinate/shikimate_5-DHase.
IPR013708; Shikimate_DHase-bd_N.
IPR006151; Shikm_DHase/Glu-tRNA_Rdtase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF01488; Shikimate_DH; 1.
PF08501; Shikimate_dh_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00507; aroE; 1.
BLOCKS Q7VUS1.
Genome annotation databases
GeneID 2665897; -.
GenomeReviews BX470248_GR; BP3004.
KEGG bpe:BP3004; -.
NMPDR fig|257313.1.peg.2652; -.
Phylogenomic databases
HOGENOM Q7VUS1; -.
Genome annotation databases
CMR Q7VUS1; BP3004.
Other
ProtoNet Q7VUS1.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   287  287     Shikimate dehydrogenase. PRO_0000325108
NP_BIND   132   136  5     NADP (By similarity). 
Sequence information
Length: 287 AA [This is the length of the unprocessed precursor] Molecular weight: 29518 Da [This is the MW of the unprocessed precursor] CRC64: 9D8D42627C6F6074 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTLPASPPRY AVIGNPIAHS RSPQIHAMFS AQTGRPLRYE RLLAPVDGFL PTVQAFRESG 

        70         80         90        100        110        120 
GLGLNVTVPF KLEAYALAEA RLSERARLAG AVNTLSWRDG AWHGCNTDGV GLVNDLLRLG 

       130        140        150        160        170        180 
VALAGARVLL VGAGGAARGV LQPLAAAGCA RIHIVNRTAA RAAELAAAWR AAAPRTGTQV 

       190        200        210        220        230        240 
SAGALAQAAE PGGWDVAINA TASGLQGAAP DLPGGLYAPD ALAYDMMYGA RPTAFMRQAE 

       250        260        270        280 
ADGAARCADG LGMLVGQAAE SFHIWHGVRP DPGPVLLALR TELLAAG 

Q7VUS1 in FASTA format

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