|
|
|
|
|
|
[1]
|
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1016/S0140-6736(00)04403-2; PubMed=11418146 [NCBI, ExPASy, EBI, Israel, Japan]
Kuroda M.,
Ohta T.,
Uchiyama I.,
Baba T.,
Yuzawa H.,
Kobayashi I.,
Cui L.,
Oguchi A.,
Aoki K.,
Nagai Y.,
Lian J.-Q.,
Ito T.,
Kanamori M.,
Matsumaru H.,
Maruyama A.,
Murakami H.,
Hosoyama A.,
Mizutani-Ui Y.,
Takahashi N.K., ![]()
Sawano T.,
Inoue R.,
Kaito C.,
Sekimizu K.,
Hirakawa H.,
Kuhara S.,
Goto S.,
Yabuzaki J.,
Kanehisa M.,
Yamashita A.,
Oshima K.,
Furuya K.,
Yoshino C.,
Shiba T.,
Hattori M.,
Ogasawara N.,
Hayashi H.,
Hiramatsu K.;
"Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
Lancet 357:1225-1240(2001).
|
[2]
|
IDENTIFICATION BY MASS SPECTROMETRY.
DOI=10.1016/j.mimet.2004.09.017; PubMed=15590099 [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A.,
Francois P.,
Bento M.,
Deshusses J.M.,
Charbonnier Y.,
Converset V.,
Huyghe A.,
Walter N.,
Hoogland C.,
Appel R.D.,
Sanchez J.-C.,
Zimmermann-Ivol C.G.,
Corthals G.L.,
Hochstrasser D.F.,
Schrenzel J.;
"Correlation of proteomic and transcriptomic profiles of Staphylococcus aureus during the post-exponential phase of growth.";
J. Microbiol. Methods 60:247-257(2005).
|
[3]
|
IDENTIFICATION BY MASS SPECTROMETRY.
Vaezzadeh A.R.,
Deshusses J.,
Lescuye P.,
Hochstrasser D.F.;
"Shotgun proteomic analysis of total and membrane protein extracts of S. aureus strain N315.";
Submitted (OCT-2007) to UniProtKB.
|
|
|
|
- FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
- CATALYTIC ACTIVITY: Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.
- COFACTOR: Thiamine pyrophosphate (By similarity).
- SUBUNIT: Heterodimer of an alpha and a beta chain.
|
|
|
|
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Length: 370 AA [This is the length of the unprocessed precursor] |
Molecular weight: 41383 Da [This is the MW of the unprocessed precursor] |
CRC64: 66BD3BF8A0C9565F [This is a checksum on the sequence] |
|
10 20 30 40 50 60
MAPKLQAQFD AVKVLNDTQS KFEMVQILDE NGNVVNEDLV PDLTDEQLVE LMERMVWTRI
70 80 90 100 110 120
LDQRSISLNR QGRLGFYAPT AGQEASQLAS QYALEKEDYI LPGYRDVPQI IWHGLPLTEA
130 140 150 160 170 180
FLFSRGHFKG NQFPEGVNAL SPQIIIGAQY IQAAGVAFAL KKRGKNAVAI TYTGDGGSSQ
190 200 210 220 230 240
GDFYEGINFA AAYKAPAIFV IQNNNYAIST PRSKQTAAET LAQKAIAVGI PGIQVDGMDA
250 260 270 280 290 300
LAVYQATKEA RDRAVAGEGP TLIETMTYRY GPHTMAGDDP TRYRTSDEDA EWEKKDPLVR
310 320 330 340 350 360
FRKFLENKGL WNEDKENEVI ERAKADIKAA IKEADNTEKQ TVTSLMEIMY EDMPQNLAEQ
370
YEIYKEKESK
|
Q820A6 in FASTA format |
|
ExPASy Home page
CBR Canada