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UniProtKB/Swiss-Prot entry Q8A7V7

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NRFA_BACTN
Primary accession number Q8A7V7
Secondary accession numbers None
Integrated into Swiss-Prot on December 12, 2006
Sequence was last modified on June 1, 2003 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 44)
Name and origin of the protein
Protein name Cytochrome c-552 [Precursor]
Synonyms EC 1.7.2.2
Ammonia-forming cytochrome c nitrite reductase
Cytochrome c nitrite reductase
Gene name
Name: nrfA
OrderedLocusNames: BT_1417
From
Bacteroides thetaiotaomicron [TaxID: 818] [HAMAP proteome]
Taxonomy Bacteria; Bacteroidetes; Bacteroidetes (class); Bacteroidales; Bacteroidaceae; Bacteroides.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482;
DOI=10.1126/science.1080029; PubMed=12663928 [NCBI, ExPASy, EBI, Israel, Japan]
Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I.;
"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis.";
Science 299:2074-2076(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE015928; AAO76524.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_810330.1; -.
3D structure databases
HSSP Q9S1E5; 1FS7. [HSSP ENTRY / PDB]
ModBase Q8A7V7.
Enzyme and pathway databases
BioCyc BTHE226186:BT_1417-MON; -.
Ontologies
GO
GO:0042597; Cellular component: periplasmic space (inferred from electronic annotation from HAMAP).
GO:0042279; Molecular function: nitrite reductase (cytochrome, ammonia-forming) activity (inferred from electronic annotation from HAMAP).
GO:0006807; Biological process: nitrogen compound metabolic process (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01182; -; 1.
PBIL [Tree]
InterPro IPR003321; Cyt_c552.
IPR011031; Multihaem_cyt.
Graphical view of domain structure.
Pfam PF02335; Cytochrom_C552; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000243; Cyt_c552; 1.
PROSITE PS51008; MULTIHEME_CYTC; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q8A7V7.
Genome annotation databases
GeneID 1071634; -.
GenomeReviews AE015928_GR; BT_1417.
KEGG bth:BT_1417; -.
NMPDR fig|226186.1.peg.1417; -.
Phylogenomic databases
HOGENOM Q8A7V7; -.
Genome annotation databases
CMR Q8A7V7; BT_1417.
Other
ProtoNet Q8A7V7.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Calcium; Complete proteome; Electron transport; Heme; Iron; Metal-binding; Oxidoreductase; Periplasm; Signal; Transport.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
SIGNAL   1    25  25     Potential. 
CHAIN   26   493  468     Cytochrome c-552. PRO_0000268960
METAL   116   116        Iron (heme 3 axial ligand) (By similarity). 
METAL   148   148        Iron (heme 1 axial ligand) (By similarity). 
METAL   186   186        Iron (heme 2 axial ligand) (By similarity). 
METAL   228   228        Iron (heme 3 axial ligand) (By similarity). 
METAL   230   230        Calcium (By similarity). 
METAL   231   231        Calcium (via carbonyl oxygen) (By similarity). 
METAL   276   276        Calcium (via carbonyl oxygen) (By similarity). 
METAL   278   278        Calcium (By similarity). 
METAL   290   290        Iron (heme 5 axial ligand) (By similarity). 
METAL   301   301        Iron (heme 4 axial ligand) (By similarity). 
METAL   315   315        Iron (heme 2 axial ligand) (By similarity). 
METAL   332   332        Iron (heme 5 axial ligand) (By similarity). 
METAL   407   407        Iron (heme 4 axial ligand) (By similarity). 
BINDING   144   144        Heme 1 (covalent) (By similarity). 
BINDING   147   147        Heme 1 (covalent) (By similarity). 
BINDING   182   182        Heme 2 (covalent) (By similarity). 
BINDING   185   185        Heme 2 (covalent) (By similarity). 
BINDING   224   224        Heme 3 (covalent) (By similarity). 
BINDING   227   227        Heme 3 (covalent) (By similarity). 
BINDING   231   231        Substrate (By similarity). 
BINDING   279   279        Substrate (By similarity). 
BINDING   297   297        Heme 4 (covalent) (By similarity). 
BINDING   300   300        Heme 4 (covalent) (By similarity). 
BINDING   328   328        Heme 5 (covalent) (By similarity). 
BINDING   331   331        Heme 5 (covalent) (By similarity). 
Sequence information
Length: 493 AA [This is the length of the unprocessed precursor] Molecular weight: 55910 Da [This is the MW of the unprocessed precursor] CRC64: BDF779458684229C [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MEKKLKSWQG WLLSGGSMVV VFVLGLCVSA LMERRAEVAS IFNNRKTVIK GIEARNELFK 

        70         80         90        100        110        120 
DDFPREYQTW TETAKTDFES EFNGNVAVDA LEKRPEMVIL WAGYAFSKDY STPRGHMHAI 

       130        140        150        160        170        180 
EDITASLRTG SPAGPHDGPQ PSTCWTCKSP DVPRMMEALG VDSFYNNKWA AFGDEIVNPI 

       190        200        210        220        230        240 
GCSDCHDPET MNLHISRPAL IEAFQRQGKD ITKATPQEMR SLVCAQCHVE YYFKGDGKYL 

       250        260        270        280        290        300 
TFPWDKGFTV EDMEAYYDEA GFYDYIHKLS RTPILKAQHP DYEIAQMGIH GQRGVSCADC 

       310        320        330        340        350        360 
HMPYKSEGGV KFSDHHIQSP LAMIDRTCQT CHRESEETLR NNVYERQRKA NEIRNRLEQE 

       370        380        390        400        410        420 
LAKAHIEAKF AWDKGATEDQ MKDVLALIRQ AQWRWDFGVA SHGGSFHAPQ EIQRILSHGL 

       430        440        450        460        470        480 
DRAMQARLAV SKVLAKHGYT EDVPMPDIST KAKAQEYIGL DMDAERAAKE KFLKTTVPAW 

       490 
LEKAKANGRL AQK
Q8A7V7 in FASTA format

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