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UniProtKB/Swiss-Prot entry Q8ERF4

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ROCA_OCEIH
Primary accession number Q8ERF4
Secondary accession numbers None
Integrated into Swiss-Prot on November 28, 2003
Sequence was last modified on March 1, 2003 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 33)
Name and origin of the protein
Protein name 1-pyrroline-5-carboxylate dehydrogenase
Synonyms P5C dehydrogenase
EC 1.5.1.12
Gene name
Name: rocA
OrderedLocusNames: OB1349
From
Oceanobacillus iheyensis [TaxID: 182710] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Oceanobacillus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=DSM 14371 / JCM 11309 / KCTC 3954 / HTE831;
DOI=10.1093/nar/gkf526; PubMed=12235376 [NCBI, ExPASy, EBI, Israel, Japan]
Takami H., Takaki Y., Uchiyama I.;
"Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments.";
Nucleic Acids Res. 30:3927-3935(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000028; BAC13305.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_692270.1; -.
3D structure databases
HSSP P51977; 1BXS. [HSSP ENTRY / PDB]
ModBase Q8ERF4.
Enzyme and pathway databases
BioCyc OIHE221109:OB1349-MON; -.
Ontologies
GO
GO:0003842; Molecular function: 1-pyrroline-5-carboxylate dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0006537; Biological process: glutamate biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00733; -; 1.
PBIL [Tree]
InterPro IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
IPR005932; d-1-pyrroline-5-COlate_DHase-2.
Graphical view of domain structure.
Gene3D G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11699; Aldehyde_dehyd; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01237; D1pyr5carbox2; 1.
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.
BLOCKS Q8ERF4.
Genome annotation databases
GeneID 1017529; -.
GenomeReviews BA000028_GR; OB1349.
KEGG oih:OB1349; -.
NMPDR fig|221109.1.peg.1355; -.
Phylogenomic databases
HOGENOM Q8ERF4; -.
Genome annotation databases
CMR Q8ERF4; OB1349.
Other
ProtoNet Q8ERF4.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   515  515     1-pyrroline-5-carboxylate dehydrogenase. PRO_0000056513
ACT_SITE   286   286        By similarity. 
ACT_SITE   320   320        By similarity. 
Sequence information
Length: 515 AA [This is the length of the unprocessed precursor] Molecular weight: 57295 Da [This is the MW of the unprocessed precursor] CRC64: 14B272164951F531 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MVLPFKHEPF TDFTVKENRK DYQDALAKVK EELGKDYPLV INGEKIYTDD KLISINPSNK 

        70         80         90        100        110        120 
NEVVGNVSKA TKQHIEEAFT SAKEAFKEWK SWSAEDRARV LYRAAAIVRR RKHEFSAWLS 

       130        140        150        160        170        180 
YDAGKPWDQA DGDTAEGIDF LEYYARHMVE LEKGKPLADR PNEDNKYFYQ PLGPGVVIPP 

       190        200        210        220        230        240 
WNFAFAIVCG TTVAPIVAGN PVLLKPSENT PVIAYKLVEV LEEAGLPKGV LNFVPGDPAE 

       250        260        270        280        290        300 
IGDYLVDHKD THFINFTGSR ATGVRIFERA TKIQDGQTHL KRIVAEMGGK DTIIVDESAD 

       310        320        330        340        350        360 
LDLAAESIVH SAFGFSGQKC SACSRAVIHE SVYDEVIEKS VELAKTLTVG NPTEDNVYMA 

       370        380        390        400        410        420 
SVVNQKQFDK IKDYIEVGKQ EGELVFGGET DDNKGFFVHP TIFKDLDPKA RIMQEEIFGP 

       430        440        450        460        470        480 
VVAFSKAKSF DELLDIANNT EYGLTGAVIS NNRENLNRAQ TEFLVGNLYF NRGCTAAIVG 

       490        500        510 
YQPFGGFKMS GTDSKAGGPD YLQHFLNAKV VTERF
Q8ERF4 in FASTA format

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