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UniProtKB/Swiss-Prot entry Q8THT2


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MTD_METAC
Primary accession number Q8THT2
Secondary accession numbers None
Integrated into Swiss-Prot on November 28, 2003
Sequence was last modified on June 1, 2002 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 37)
Name and origin of the protein
Protein name F420-dependent methylenetetrahydromethanopterin dehydrogenase
Synonyms MTD
EC 1.5.99.9
Coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase
Gene name
Name: mtd
OrderedLocusNames: MA_4430
From
Methanosarcina acetivorans [TaxID: 2214] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A;
DOI=10.1101/gr.223902; PubMed=11932238 [NCBI, ExPASy, EBI, Israel, Japan]
Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W., Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J., Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P., McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D., Cann I., Graham D.E., Grahame D.A., Guss A.M., Hedderich R., Ingram-Smith C., Kuettner H.C., Krzycki J.A., Leigh J.A., Li W., Liu J., Mukhopadhyay B., Reeve J.N., Smith K., Springer T.A., Umayam L.A., White O., White R.H., de Macario E.C., Ferry J.G., Jarrell K.F., Jing H., Macario A.J.L., Paulsen I.T., Pritchett M., Sowers K.R., Swanson R.V., Zinder S.H., Lander E., Metcalf W.W., Birren B.;
"The genome of Methanosarcina acetivorans reveals extensive metabolic and physiological diversity.";
Genome Res. 12:532-542(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE010299; AAM07771.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_619291.1; -.
3D structure databases
ModBase Q8THT2.
Enzyme and pathway databases
BioCyc MACE188937:MA4430-MON; -.
Ontologies
GO
GO:0030268; Molecular function: methylenetetrahydromethanopterin dehydrogenase activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00058; -; 1.
PBIL [Tree]
InterPro IPR002844; Methylene_DHase.
Graphical view of domain structure.
Pfam PF01993; MTD; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF005627; MTD; 1.
BLOCKS Q8THT2.
Genome annotation databases
GeneID 1476324; -.
GenomeReviews AE010299_GR; MA_4430.
KEGG mac:MA4430; -.
NMPDR fig|188937.1.peg.4317; -.
Phylogenomic databases
HOGENOM Q8THT2; -.
Genome annotation databases
CMR Q8THT2; MA_4430.
Other
ProtoNet Q8THT2.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Methanogenesis; One-carbon metabolism; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   279  279     F420-dependent methylenetetrahydromethanopterin dehydrogenase. PRO_0000075037
Sequence information
Length: 279 AA [This is the length of the unprocessed precursor] Molecular weight: 30268 Da [This is the MW of the unprocessed precursor] CRC64: 2AB2991081836567 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MRKMVNIGFI KMGNLGMSQV INLIQDEIAA REGITVRVFG TGAKMGPADA ADTESFKQWN 

        70         80         90        100        110        120 
ADFVVMISPN AAAPGPTAAR EIWKDVPCIV VSDGPTKKEA REALEQEGFG YIILPVDPLI 

       130        140        150        160        170        180 
GAKREFLDPV EMASFNSDAM KVLSSCGVVR LIQEELDRVT EQVASGKSGE DLELPHIFAK 

       190        200        210        220        230        240 
PEKCVEHAGF ANPYAKAKAL AALHMAEKVA QVNFPACFML KEVEQVCLTA AAGHEIMGAA 

       250        260        270 
AILATQAREI EKSNDTVFRQ PHAKNGTLLK KVKLYEKPE 

Q8THT2 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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