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UniProtKB/Swiss-Prot entry Q8UJC5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AROE_AGRT5
Primary accession number Q8UJC5
Secondary accession numbers None
Integrated into Swiss-Prot on October 19, 2002
Sequence was last modified on October 19, 2002 (Sequence version 2)
Annotations were last modified on    July 22, 2008 (Entry version 42)
Name and origin of the protein
Protein name Shikimate dehydrogenase
Synonym EC 1.1.1.25
Gene name
Name: aroE
OrderedLocusNames: Atu0003
ORFNames: AGR_C_3
From
Agrobacterium tumefaciens (strain C58 / ATCC 33970) [TaxID: 176299] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1066804; PubMed=11743193 [NCBI, ExPASy, EBI, Israel, Japan]
Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K., Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y., Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P., Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R., Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G., Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y., Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S., Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F., Gordon M.P., Olson M.V., Nester E.W.;
"The genome of the natural genetic engineer Agrobacterium tumefaciens C58.";
Science 294:2317-2323(2001).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1066803; PubMed=11743194 [NCBI, ExPASy, EBI, Israel, Japan]
Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B., Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K., Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M., Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C., Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
"Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58.";
Science 294:2323-2328(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE007869; AAK85828.2; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR AD2577; AD2577.
C97359; C97359.
RefSeq NP_353043.2; -.
3D structure databases
HSSP Q58484; 1NVT. [HSSP ENTRY / PDB]
ModBase Q8UJC5.
Ontologies
GO
GO:0004764; Molecular function: shikimate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0009073; Biological process: aromatic amino acid family biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00222; -; 1.
PBIL [Tree]
InterPro IPR016040; NAD(P)-bd.
IPR011342; Quinate/shikimate_5-DHase.
IPR013708; Shikimate_DHase-bd_N.
IPR006151; Shikm_DHase/Glu-tRNA_Rdtase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF01488; Shikimate_DH; 1.
PF08501; Shikimate_dh_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00507; aroE; 1.
BLOCKS Q8UJC5.
Genome annotation databases
GeneID 1132041; -.
GenomeReviews AE007869_GR; Atu0003.
KEGG atc:AGR_C_3; -.
atu:Atu0003; -.
Phylogenomic databases
HOGENOM Q8UJC5; -.
Genome annotation databases
CMR Q8UJC5; Atu0003.
Other
ProtoNet Q8UJC5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   286  286     Shikimate dehydrogenase. PRO_0000135988
NP_BIND   137   141  5     NADP (By similarity). 
Sequence information
Length: 286 AA [This is the length of the unprocessed precursor] Molecular weight: 31237 Da [This is the MW of the unprocessed precursor] CRC64: A099CE911F493D3C [This is a checksum on the sequence]
        10         20         30         40         50         60 
MADSRETLTI NAFVVGYPIK HSRSPIIHSY WLKKFGIAGS YTAVEVSPDD FPKFIATLKE 

        70         80         90        100        110        120 
GKPGAAVGGN ATIPHKEAAY RLADHPDALA EELGAANTIW MEEGKLHATN TDGYGFVSNL 

       130        140        150        160        170        180 
DERHPGWDKT QRAVVFGAGG ASRAVIQSLR DRDVAEIHVV NRTVERAREL ADRFGPRVFS 

       190        200        210        220        230        240 
HPQAALQEVM HGAGLFVNTT SLGMNGTEAP HLDFSHLAAN AVVTDIVYVP LKTPILNMAQ 

       250        260        270        280 
EQGIATVDGL GMLLHQAKPG FRRWFGRIPE VDETLRSLII ADMEKH 

Q8UJC5 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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