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UniProtKB/Swiss-Prot entry Q8X182


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CATA2_NEUCR
Primary accession number Q8X182
Secondary accession number Q7S4Q3
Integrated into Swiss-Prot on May 9, 2003
Sequence was last modified on October 1, 2002 (Sequence version 2)
Annotations were last modified on    September 2, 2008 (Entry version 52)
Name and origin of the protein
Protein name Peroxidase/catalase 2
Synonyms EC 1.11.1.6
EC 1.11.1.7
Catalase-peroxidase 2
Gene name
Name: cat-2
ORFNames: NCU05770
From
Neurospora crassa [TaxID: 5141] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes; Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [MRNA].
DOI=10.1515/BC.2002.058; PubMed=12033445 [NCBI, ExPASy, EBI, Israel, Japan]
Peraza L., Hansberg W.;
"Neurospora crassa catalases, singlet oxygen and cell differentiation.";
Biol. Chem. 383:569-575(2002).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
DOI=10.1038/nature01554; PubMed=12712197 [NCBI, ExPASy, EBI, Israel, Japan]
Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B., Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M., Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U., Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D., Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S., Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D., Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S., Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A., DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R., Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R., Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
"The genome sequence of the filamentous fungus Neurospora crassa.";
Nature 422:859-868(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF459787; AAL66352.2; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AABX02000023; EAA30509.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_959745.1; -.
3D structure databases
HSSP O59651; 1ITK. [HSSP ENTRY / PDB]
ModBase Q8X182.
Protein family/group databases
PeroxiBase 2181; NcCP01.
Enzyme and pathway databases
BioCyc NCRA-XX3-01:NCRA-XX3-01-009518-MON; -.
Family and domain databases
InterPro IPR000763; Catalase_proxase.
IPR002016; Haem_peroxidase_pln/fun/bac.
Graphical view of domain structure.
Pfam PF00141; peroxidase; 2.
Pfam graphical view of domain structure.
PRINTS PR00460; BPEROXIDASE.
PR00458; PEROXIDASE.
TIGRFAMs TIGR00198; cat_per_HPI; 1.
PROSITE PS00435; PEROXIDASE_1; 1.
PS00436; PEROXIDASE_2; 1.
PS50873; PEROXIDASE_4; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q8X182.
Genome annotation databases
GeneID 3875883; -.
KEGG ncr:NCU05770; -.
NMPDR fig|5141.1.peg.3558; -.
Other
ProtoNet Q8X182.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Heme; Hydrogen peroxide; Iron; Metal-binding; Oxidoreductase; Peroxidase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   753  753     Peroxidase/catalase 2. PRO_0000055582
ACT_SITE   91    91        Proton acceptor (By similarity). 
METAL   279   279        Iron (heme axial ligand) (By similarity). 
SITE   87    87  1     Transition state stabilizer (By similarity). 
CROSSLNK   90   238        Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-264) (By similarity). 
CROSSLNK   238   264        Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-90) (By similarity). 
Sequence information
Length: 753 AA [This is the length of the unprocessed precursor] Molecular weight: 83380 Da [This is the MW of the unprocessed precursor] CRC64: DED01DC6D10BA582 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSECPVRKSN VGGGGTRNHD WWPAQLRLNI LRQHTPVSNP LDKDFDYAAA FKSLDYEGLK 

        70         80         90        100        110        120 
KDLTKLMTDS QDWWPADFGH YGGLFIRMAW HSAGTYRVTD GRGGGGEGQQ RFAPLNSWPD 

       130        140        150        160        170        180 
NVSLDKARRL LWPIKQKYGN KISWSDLLLL TGNVALESMG FKTFGFAGGR PDTWEADESV 

       190        200        210        220        230        240 
YWGAETTWLG NEDRYSEGQE GHEGHGVVQG DESKKQHTDI HNRDLQSPLA SSHMGLIYVN 

       250        260        270        280        290        300 
PEGPDGIPDP VASAKDIRVT FGRMAMNDEE TVALIAGGHS FGKTHGAGPT HHVGKEPEAA 

       310        320        330        340        350        360 
PIEHQGLGWA NSFGQGKGPD TITSGLEVTW TPTPTKWGMG YLEYLYKFDW EPTKSPAGAN 

       370        380        390        400        410        420 
QWVAKNAEPT IPDAYDPNKK KLPTMLTTDI ALRMDPAYDK ICRDYLANPD KFADAFARAW 

       430        440        450        460        470        480 
FKLLHRDMGP RTRWIGPEVP SEILPWEDYI PPVDYQIIDD NDIAALKKEI LATGVAPKKL 

       490        500        510        520        530        540 
IFVAWSSASS FRGSDKRGGA NGARIRLAPQ NEWKVNDPST LREVLAALES VQQKFNDSSS 

       550        560        570        580        590        600 
GKKVSLADLI VLGGVAALEQ ASGLVVPFTP GRNDATQEHT DVHSFTHLEP HADGFRSYGK 

       610        620        630        640        650        660 
GTKRVRTEQF LIDRASLLTL SAPELTALIG GLRVLEANYD GSSYGVLTKT PGKLTNDYFV 

       670        680        690        700        710        720 
NLLDTNTAWK AADNEGEVFI GYDRKTHDKK WTATRADLIF GAHAELRALA EVYAAVDGEE 

       730        740        750 
KFKRDFVAAW HKVMNLDRFD LKQEGRGQNA PKL 

Q8X182 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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