[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Zhang Z., Gurr S.J.; "Isolation and characterization of a Blumeria graminis catalase gene involved in antioxidant action in barley/powdery mildew interactions."; Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases.

Comments

FUNCTION: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
CATALYTIC ACTIVITY: 2 H₂O₂ = O₂ + 2 H₂O.
COFACTOR: Heme group.
SIMILARITY: Belongs to the catalase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AF327335; AAL56982.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

HSSP

P21179; 1CF9. [HSSP ENTRY / PDB]

ModBase

Q8X1P0.

Family and domain databases

InterPro

IPR002226; Catalase.
IPR010582; Catalase-rel.
IPR011614; Catalase_N.
Graphical view of domain structure.

Gene3D

G3DSA:2.40.180.10; Catalase_N; 1.

PANTHER

PTHR11465; Catalase; 1.

Pfam

PF00199; Catalase; 1.
PF06628; Catalase-rel; 1.
Pfam graphical view of domain structure.

PRINTS

PR00067; CATALASE.

ProDom

PD000510; Catalase; 1.
[Domain structure / List of seq. sharing at least 1 domain]

PROSITE

PS00437; CATALASE_1; FALSE_NEG.
PS00438; CATALASE_2; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Heme; Hydrogen peroxide; Iron; Metal-binding; Oxidoreductase; Peroxidase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 718`	`718`	`Catalase.`	`PRO_0000084922`
`ACT_SITE`	`103 103`		`By similarity.`
`ACT_SITE`	`176 176`		`By similarity.`
`METAL`	`390 390`		`Iron (heme axial ligand) (By similarity).`

Sequence information

Length: 718 AA [This is the length of the unprocessed precursor]

Molecular weight: 79011 Da [This is the MW of the unprocessed precursor]

CRC64: 31F4135D69A42544 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MRLSLWNLLG LSGLVVASCP YMSGEDQEYH ISHIQARGTD SEFLDQFKVE DSNSYLTTDA 

        70         80         90        100        110        120 
GGPIQDDASL KAGERGPTLL EDFIFRQKIQ HFDHERVPER AVHARGAGAY GTFTSYADWT 

       130        140        150        160        170        180 
NITAASFLNS KGKETPVFVR FSTVAGSRGS ADTVRDVHGF ATRFYTDEGN FDIVGNNIPV 

       190        200        210        220        230        240 
FFIQDAILFP DLVHAVKPSP DSEIPQAATG HDSAWDFFSQ QPSTLHTLFW AMSGHGIPRS 

       250        260        270        280        290        300 
YRHMDGFGVH TMRLVTDDGK SKLVKWHWKT KQGKASLVWE EAQILAGKNP DFHRQDLWDD 

       310        320        330        340        350        360 
INAGNGPEWE LGVQIVDEED VQAFGFDLLD PTKFLPEELV PVTILGKMKL TDNPTNYFAE 

       370        380        390        400        410        420 
TEQVMFQPGH IVRGVDFSDD PLLQGRIYSY LDTQLNRNGG PNFEQLPVNR PRTKVHNNNR 

       430        440        450        460        470        480 
DGAGQMFIHT NKAPYSPNSL SGGNPKQANQ TKGRGFFTAP SRKVVGSLHR GTASSFADVW 

       490        500        510        520        530        540 
SQPRMFYNSL IPSEQQFLVN AIRFEISQLK SDLIKKNTLM QLNRVSNDLA TRVAAVIGYK 

       550        560        570        580        590        600 
PLDPSPEFYT NATTDYVTIF GKPLPSVVGF TVGILASTSS STSISQAAQL ATSFSSRGIR 

       610        620        630        640        650        660 
AVIVGESLLS GTDQTYSSAD ATAFDAVVVT MGAETLFGPV AKPNTLFPSG RPSQILHDAY 

       670        680        690        700        710 
RWGKPVGAVS KASVVLEPLP GTKNQGGVYR VESVNELATS IAKGLETFRF VDRFPLDS

Q8X1P0 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools