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UniProtKB/Swiss-Prot entry Q8XRZ0

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HGD_RALSO
Primary accession number Q8XRZ0
Secondary accession numbers None
Integrated into Swiss-Prot on May 27, 2002
Sequence was last modified on March 1, 2002 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 37)
Name and origin of the protein
Protein name Homogentisate 1,2-dioxygenase
Synonyms EC 1.13.11.5
Homogentisicase
Homogentisate oxygenase
Homogentisic acid oxidase
Gene name
Name: hmgA
OrderedLocusNames: RSp0691
ORFNames: RS01758
From
Ralstonia solanacearum (Pseudomonas solanacearum) [TaxID: 305] [HAMAP proteome]
Encoded on Plasmid megaplasmid Rsp.
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Burkholderiaceae; Ralstonia.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=GMI1000;
DOI=10.1038/415497a; PubMed=11823852 [NCBI, ExPASy, EBI, Israel, Japan]
Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M., Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M., Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M., Moisan A., Robert C., Saurin W., Schiex T., Siguier P., Thebault P., Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A.;
"Genome sequence of the plant pathogen Ralstonia solanacearum.";
Nature 415:497-502(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL646053; CAD17842.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_522252.1; -.
3D structure databases
ModBase Q8XRZ0.
Enzyme and pathway databases
BioCyc RSOL267608:RSP0691-MON; -.
Ontologies
GO
GO:0004411; Molecular function: homogentisate 1,2-dioxygenase activity (inferred from electronic annotation from HAMAP).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from HAMAP).
GO:0006559; Biological process: L-phenylalanine catabolic process (inferred from electronic annotation from HAMAP).
GO:0006572; Biological process: tyrosine catabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00334; -; 1.
PBIL [Tree]
InterPro IPR005708; Homogentis_dOase.
Graphical view of domain structure.
PANTHER PTHR11056; Homogentis_dOase; 1.
Pfam PF04209; HgmA; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01015; hmgA; 1.
BLOCKS Q8XRZ0.
Genome annotation databases
GeneID 1222998; -.
GenomeReviews AL646053_GR; RSp0691.
KEGG rso:RSp0691; -.
NMPDR fig|267608.1.peg.4131; -.
Phylogenomic databases
HOGENOM Q8XRZ0; -.
Genome annotation databases
CMR Q8XRZ0; RSp0691.
Other
ProtoNet Q8XRZ0.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Dioxygenase; Iron; Metal-binding; Oxidoreductase; Phenylalanine catabolism; Plasmid; Tyrosine catabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   448  448     Homogentisate 1,2-dioxygenase. PRO_0000220252
METAL   345   345        Iron (By similarity). 
METAL   351   351        Iron (By similarity). 
METAL   381   381        Iron (By similarity). 
Sequence information
Length: 448 AA [This is the length of the unprocessed precursor] Molecular weight: 49537 Da [This is the MW of the unprocessed precursor] CRC64: 6467FE12F70996D5 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MNMLAPAAKN AFTPASPDRP AYQSGFGNEF ATEALPGALP HGQNSPQQAP YGLYAEQLSG 

        70         80         90        100        110        120 
TAFTAPRAHN RRAWLYRIRP AAVHLPFEPI AQDRFHSDFH AVPASPNQLR WDPLPAPAAG 

       130        140        150        160        170        180 
TDFIDGIVTF AGNGGPDAQT GCGIHLYAAN ASMTGRFFYN ADGELLIVPQ QGRLRLLTEL 

       190        200        210        220        230        240 
GVLDVEPLEI AVIPRGVRFR VELPDGEARG YLCENFGAIF RLPDLGVIGS NGLANPRDFL 

       250        260        270        280        290        300 
TPHAWYEDRE GDFELVAKFH GNLWRARIGH SPLDVVAWHG NYAPYKYDLR LFNTIGSISY 

       310        320        330        340        350        360 
DHPDPSIFLV LQSVSDTPGV DAIDFVIFPP RWLAMEHSFR PPWFHRNIAS EFMGLIQGVY 

       370        380        390        400        410        420 
DAKAEGFVPG GASLHNCMTG HGPDAETFEK ASHADTTQPH KVEATMAFMF ETRGVIRPTR 

       430        440 
FAAESAQLQA RYFECWQGLK KHFDPAKR
Q8XRZ0 in FASTA format

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