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UniProtKB/Swiss-Prot entry Q8XU39


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PH4H_RALSO
Primary accession number Q8XU39
Secondary accession numbers None
Integrated into Swiss-Prot on April 16, 2002
Sequence was last modified on March 1, 2002 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 47)
Name and origin of the protein
Protein name Phenylalanine-4-hydroxylase
Synonyms PAH
EC 1.14.16.1
Phe-4-monooxygenase
Gene name
Name: phhA
OrderedLocusNames: RSc3355
ORFNames: RS02630
From
Ralstonia solanacearum (Pseudomonas solanacearum) [TaxID: 305] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Burkholderiaceae; Ralstonia.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=GMI1000;
DOI=10.1038/415497a; PubMed=11823852 [NCBI, ExPASy, EBI, Israel, Japan]
Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M., Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M., Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M., Moisan A., Robert C., Saurin W., Schiex T., Siguier P., Thebault P., Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A.;
"Genome sequence of the plant pathogen Ralstonia solanacearum.";
Nature 415:497-502(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL646052; CAD17143.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_521474.1; -.
3D structure databases
HSSP P30967; 1LTZ. [HSSP ENTRY / PDB]
SMR Q8XU39; 42-301.
ModBase Q8XU39.
Enzyme and pathway databases
BioCyc RSOL267608:RSC3355-MON; -.
Family and domain databases
InterPro IPR001273; Aaa_hydroxylase.
IPR005960; Phe-4-hydroxylase_mono.
Graphical view of domain structure.
Gene3D G3DSA:1.10.800.10; Aaa_hydroxylase; 1.
PANTHER PTHR11473; Aaa_hydroxylase; 1.
Pfam PF00351; Biopterin_H; 1.
Pfam graphical view of domain structure.
PRINTS PR00372; FYWHYDRXLASE.
ProDom PD002559; Aaa_hydroxylase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR01267; Phe4hydrox_mono; 1.
PROSITE PS00367; BIOPTERIN_HYDROXYL; 1.
BLOCKS Q8XU39.
Genome annotation databases
GeneID 1222219; -.
GenomeReviews AL646052_GR; RSc3355.
KEGG rso:RSc3355; -.
NMPDR fig|267608.1.peg.3353; -.
Phylogenomic databases
HOGENOM Q8XU39; -.
Genome annotation databases
CMR Q8XU39; RSc3355.
Other
ProtoNet Q8XU39.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Iron; Metal-binding; Monooxygenase; Oxidoreductase; Phenylalanine catabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   313  313     Phenylalanine-4-hydroxylase. PRO_0000205556
METAL   154   154        Iron (Potential). 
METAL   159   159        Iron (Potential). 
METAL   200   200        Iron (Potential). 
Sequence information
Length: 313 AA [This is the length of the unprocessed precursor] Molecular weight: 34901 Da [This is the MW of the unprocessed precursor] CRC64: 2EBA9E216476371B [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAIATPTSAA PTPAPAGFTG TLTDKLREQF AEGLDGQTLR PDFTMEQPVH RYTAADHATW 

        70         80         90        100        110        120 
RTLYDRQEAL LPGRACDEFL QGLSTLGMSR EGVPSFDRLN ETLMRATGWQ IVAVPGLVPD 

       130        140        150        160        170        180 
EVFFEHLANR RFPASWWMRR PDQLDYLQEP DGFHDIFGHV PLLINPVFAD YMQAYGQGGL 

       190        200        210        220        230        240 
KAARLGALDM LARLYWYTVE FGLIRTPAGL RIYGAGIVSS KSESVYALDS ASPNRIGFDV 

       250        260        270        280        290        300 
HRIMRTRYRI DTFQKTYFVI DSFEQLFDAT RPDFTPLYEA LGTLPTFGAG DVVDGDAVLN 

       310 
AGTREGWADT ADI 

Q8XU39 in FASTA format

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