ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q8ZBN7


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name CYSI_YERPE
Primary accession number Q8ZBN7
Secondary accession numbers Q0WBS5 Q74XS4 Q7CKC9
Integrated into Swiss-Prot on September 13, 2005
Sequence was last modified on March 1, 2002 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 41)
Name and origin of the protein
Protein name Sulfite reductase [NADPH] hemoprotein beta-component
Synonyms SIR-HP
SIRHP
EC 1.8.1.2
Gene name
Name: cysI
OrderedLocusNames: YPO3371, y0819, YP_0315
From
Yersinia pestis [TaxID: 632] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Yersinia.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CO-92 / Biovar Orientalis;
DOI=10.1038/35097083; PubMed=11586360 [NCBI, ExPASy, EBI, Israel, Japan]
Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G., Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L., Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M., Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T., Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S., Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G.;
"Genome sequence of Yersinia pestis, the causative agent of plague.";
Nature 413:523-527(2001).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=KIM5 / Biovar Mediaevalis;
DOI=10.1128/JB.184.16.4601-4611.2002; PubMed=12142430 [NCBI, ExPASy, EBI, Israel, Japan]
Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P., Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D., Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A., Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
"Genome sequence of Yersinia pestis KIM.";
J. Bacteriol. 184:4601-4611(2002).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=91001 / Biovar Mediaevalis;
DOI=10.1093/dnares/11.3.179; PubMed=15368893 [NCBI, ExPASy, EBI, Israel, Japan]
Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.;
"Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans.";
DNA Res. 11:179-197(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL590842; CAL21960.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE009952; AAM84406.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE017042; AAS60590.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR AE0409; AE0409.
RefSeq NP_668155.1; -.
NP_991713.1; -.
3D structure databases
HSSP P17846; 7GEP. [HSSP ENTRY / PDB]
SMR Q8ZBN7; 81-571.
ModBase Q8ZBN7.
Enzyme and pathway databases
BioCyc YPES187410:Y0819-MON; -.
YPES214092:YPO3371-MON; -.
YPES229193:YP0315-MON; -.
Ontologies
GO
GO:0004783; Molecular function: sulfite reductase (NADPH) activity (inferred from electronic annotation from HAMAP).
GO:0000103; Biological process: sulfate assimilation (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01540; -; 1.
PBIL [Tree]
InterPro IPR011786; CysI.
IPR006066; Nir_Si_BS.
IPR006067; Nir_Sir_4Fe4S.
IPR005117; NiRdtase/SiRdtase_haem-b_fer.
Graphical view of domain structure.
Pfam PF01077; NIR_SIR; 1.
PF03460; NIR_SIR_ferr; 2.
Pfam graphical view of domain structure.
PRINTS PR00397; SIROHAEM.
TIGRFAMs TIGR02041; CysI; 1.
PROSITE PS00365; NIR_SIR; 1.
BLOCKS Q8ZBN7.
Genome annotation databases
GeneID 1145766; -.
2763488; -.
GenomeReviews AE009952_GR; y0819.
AE017042_GR; YP_0315.
AL590842_GR; YPO3371.
KEGG ype:YPO3371; -.
ypk:y0819; -.
ypm:YP_0315; -.
Phylogenomic databases
HOGENOM Q8ZBN7; -.
Genome annotation databases
CMR Q8ZBN7; YPO3371.
Other
ProtoNet Q8ZBN7.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
4Fe-4S; Amino-acid biosynthesis; Complete proteome; Cysteine biosynthesis; Heme; Iron; Iron-sulfur; Metal-binding; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   576  576     Sulfite reductase [NADPH] hemoprotein beta-component. PRO_0000199917
METAL   435   435        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   441   441        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   480   480        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   484   484        Iron (siroheme axial ligand) (By similarity). 
METAL   484   484        Iron-sulfur (4Fe-4S) (By similarity). 
Sequence information
Length: 576 AA [This is the length of the unprocessed precursor] Molecular weight: 64076 Da [This is the MW of the unprocessed precursor] CRC64: 28AA6EF7463B6B87 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MNEKHPGPLV VSGKLSDGER MKSESNFLRG TIAEDLNNGL TGGFSGDNFL LIRFHGMYQQ 

        70         80         90        100        110        120 
DDRDIRAERA EQKLEPRHAM MLRCRLPGGI ITPQQWLGID KFAADNTLYG SIRITNRQTF 

       130        140        150        160        170        180 
QFHGILKGNV KPAHQLLNEL GLDALATAND VNRNVLCTSN PVESALHQEA YEWAKKISEH 

       190        200        210        220        230        240 
LLPRTRAYAE IWLDAEKVAT TDEEPILGAT YLPRKFKTTV VIPPQNDVDL HANDLNFVAV 

       250        260        270        280        290        300 
ADKGKLIGFN VLVGGGLSIA HGDKNTYPRK ASEFGYIPLK HTLAIAEAVV TTQRDWGNRT 

       310        320        330        340        350        360 
DRKNAKTKYT LERVGVETFK AEVEKRAGVS FSAIKPYQFI GRGDRIGWVK GVDKKWHLTL 

       370        380        390        400        410        420 
FVENGRLLDY PGRSLKTGVA EIAKIHQGDF RLTANQNLIV AGVPEKDKAR IEALAREHGL 

       430        440        450        460        470        480 
MDDNVTSQRE NSMACVSFPT CPLAMAEAER FLPEFVTRVE GILQQHGLAD EHIVLRVTGC 

       490        500        510        520        530        540 
PNGCGRALLA EVGLVGKAVG RYNLHLGGNR EGTRIPRMYR ENITADEILL ITDQLVGRWA 

       550        560        570 
KERHVDEGFG DFVIRAGVIA PVIDSARDFY DVQEAM 

Q8ZBN7 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by ca flag CBR Canada Mirror sites: Australia  Brazil  China  Korea  Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!