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UniProtKB/Swiss-Prot entry Q922Q4

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name P5CR2_MOUSE
Primary accession number Q922Q4
Secondary accession numbers None
Integrated into Swiss-Prot on March 1, 2005
Sequence was last modified on December 1, 2001 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 45)
Name and origin of the protein
Protein name Pyrroline-5-carboxylate reductase 2
Synonyms P5C reductase 2
P5CR 2
EC 1.5.1.2
Gene name
Name: Pycr2
From
Mus musculus (Mouse) [TaxID: 10090] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=FVB/N;
TISSUE=Mammary tumor;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BC006882; AAH06882.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_598466.1; -.
UniGene Mm.274180
3D structure databases
SMR Q922Q4; 1-275.
ModBase Q922Q4.
Organism-specific databases
MGI MGI:1277956; Pycr2.
Gene expression databases
ArrayExpress Q922Q4; -.
GermOnline ENSMUSG00000026520; Mus musculus.
Family and domain databases
InterPro IPR016040; NAD(P)-bd.
IPR004455; NADP_OxRdtase_F420.
IPR000304; P5CR.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR11645; P5CR; 1.
Pfam PF03807; F420_oxidored; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000193; Pyrrol-5-carb_rd; 1.
TIGRFAMs TIGR00112; proC; 1.
PROSITE PS00521; P5CR; 1.
BLOCKS Q922Q4.
Genome annotation databases
Ensembl ENSMUSG00000026520; Mus musculus. [Contig view]
GeneID 69051; -.
KEGG mmu:69051; -.
Phylogenomic databases
HOGENOM Q922Q4; -.
HOVERGEN Q922Q4; -.
Other
SOURCE Pycr2; Mus musculus.
ProtoNet Q922Q4.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; NADP; Oxidoreductase; Proline biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   320  320     Pyrroline-5-carboxylate reductase 2. PRO_0000187318
Sequence information
Length: 320 AA [This is the length of the unprocessed precursor] Molecular weight: 33659 Da [This is the MW of the unprocessed precursor] CRC64: 64DD7F96FB8C4BC5 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSVGFIGAGQ LACALARGFT AAGVLSAHKI IASSPDMDLP TVSALRRMGV NLTRSNKDTV 

        70         80         90        100        110        120 
RHSDVLFLAV KPHIIPFILD EIGADVQERH IVVSCAAGVT ISSVEKKLMA FQPAPKVIRC 

       130        140        150        160        170        180 
MTNTPVVVRE GATVYATGTH ALVEDGKLLE QLMSSVGFCT EVEEDLIDAI TGLSGSGPAY 

       190        200        210        220        230        240 
AFMALDALAD GGVKMGVPRR LAVRLGAQAL LGAAKMLLDS EDHPGQLKDN VCSPGGATIH 

       250        260        270        280        290        300 
ALHFLESGGF RSLLINAVEA SCIRTRELQS MADQEKVSPA ALKKTLLDRV KLESPTVSTL 

       310        320 
APPSSGKLLT RNPAQGSKKE
Q922Q4 in FASTA format

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