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UniProtKB/Swiss-Prot entry Q92RY3


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name FOLD2_RHIME
Primary accession number Q92RY3
Secondary accession numbers None
Integrated into Swiss-Prot on December 12, 2006
Sequence was last modified on December 1, 2001 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 36)
Name and origin of the protein
Protein name Bifunctional protein folD 2
Synonyms None
Includes Methylenetetrahydrofolate dehydrogenase
     (EC 1.5.1.5)
Methenyltetrahydrofolate cyclohydrolase
     (EC 3.5.4.9)
Gene name
Name: folD2
OrderedLocusNames: R00693
ORFNames: SMc03059
From
Rhizobium meliloti (Sinorhizobium meliloti) [TaxID: 382] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=1021;
DOI=10.1073/pnas.161294398; PubMed=11481430 [NCBI, ExPASy, EBI, Israel, Japan]
Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J., Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S., Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T., Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C., Thebault P., Vandenbol M., Weidner S., Galibert F.;
"Analysis of the chromosome sequence of the legume symbiont Sinorhizobium meliloti strain 1021.";
Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL591688; CAC45265.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_384799.1; -.
3D structure databases
HSSP P11586; 1A4I. [HSSP ENTRY / PDB]
ModBase Q92RY3.
Enzyme and pathway databases
BioCyc SMEL266834:SMC03059-MON; -.
Ontologies
GO
GO:0004477; Molecular function: methenyltetrahydrofolate cyclohydrolase activity (inferred from electronic annotation from HAMAP).
GO:0004488; Molecular function: methylenetetrahydrofolate dehydrogenase (NADP+) activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01576; -; 1.
PBIL [Tree]
InterPro IPR016040; NAD(P)-bd.
IPR000672; THF_DHase/CycOHase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF00763; THF_DHG_CYH; 1.
PF02882; THF_DHG_CYH_C; 1.
Pfam graphical view of domain structure.
PRINTS PR00085; THFDHDRGNASE.
ProDom PD002300; THFDhg/Cyc_hydro; 1.
[Domain structure / List of seq. sharing at least 1 domain]
PROSITE PS00766; THF_DHG_CYH_1; FALSE_NEG.
PS00767; THF_DHG_CYH_2; 1.
BLOCKS Q92RY3.
Genome annotation databases
GeneID 1232332; -.
GenomeReviews AL591688_GR; R00693.
KEGG sme:SMc03059; -.
NMPDR fig|266834.1.peg.1987; -.
Phylogenomic databases
HOGENOM Q92RY3; -.
Genome annotation databases
CMR Q92RY3; R00693.
Other
ProtoNet Q92RY3.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Histidine biosynthesis; Hydrolase; Methionine biosynthesis; Multifunctional enzyme; NADP; One-carbon metabolism; Oxidoreductase; Purine biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   299  299     Bifunctional protein folD 2. PRO_0000268466
Sequence information
Length: 299 AA [This is the length of the unprocessed precursor] Molecular weight: 31028 Da [This is the MW of the unprocessed precursor] CRC64: 2A3875AB26480F99 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTTVIDGKNV AASVIETVKS ATSALESETG VRAGLAVVIV GDDPASHTYV SAKSRMAKEC 

        70         80         90        100        110        120 
GFLSVQHTLP EETSQEELAA LVAELNADPS IHGILVQLPL PKHLRSEPII QSILPEKDVD 

       130        140        150        160        170        180 
GLHVVNAGKL ATGDLEGGLV SCTPAGAMVF VRRTYGDDLS GLNAVVIGRS NLFGKPMSAL 

       190        200        210        220        230        240 
LLAANATVTT AHSRTKDLAA VCRNADILVA AVGRPEMVKA DWVKPGAMVV DVGINRVPAP 

       250        260        270        280        290 
ERGEGRTKLV GDVAFDECAK VAGVITPVPG GVGPMTIAML MANTIIAACR MAGRKPPKF 

Q92RY3 in FASTA format

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