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UniProtKB/Swiss-Prot entry Q97BJ8

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G3P_THEVO
Primary accession number Q97BJ8
Secondary accession numbers None
Integrated into Swiss-Prot on May 27, 2002
Sequence was last modified on October 1, 2001 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 48)
Name and origin of the protein
Protein name Glyceraldehyde-3-phosphate dehydrogenase
Synonyms GAPDH
EC 1.2.1.59
NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase
Gene name
Name: gap
OrderedLocusNames: TV0457
ORFNames: TVG0444310
From
Thermoplasma volcanium [TaxID: 50339] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Thermoplasmata; Thermoplasmatales; Thermoplasmataceae; Thermoplasma.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 51530 / DSM 4299 / IFO 15438 / JCM 9571 / GSS1;
DOI=10.1073/pnas.97.26.14257; PubMed=11121031 [NCBI, ExPASy, EBI, Israel, Japan]
Kawashima T., Amano N., Koike H., Makino S., Higuchi S., Kawashima-Ohya Y., Watanabe K., Yamazaki M., Kanehori K., Kawamoto T., Nunoshiba T., Yamamoto Y., Aramaki H., Makino K., Suzuki M.;
"Archaeal adaptation to higher temperatures revealed by genomic sequence of Thermoplasma volcanium.";
Proc. Natl. Acad. Sci. U.S.A. 97:14257-14262(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000011; BAB59599.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_110977.1; -.
3D structure databases
HSSP P10618; 1CF2. [HSSP ENTRY / PDB]
ModBase Q97BJ8.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004365; Molecular function: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity (inferred from electronic annotation from HAMAP).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00559; -; 1.
PBIL [Tree]
InterPro IPR000173; GlycerAld_3-P_DHase.
IPR006436; Glyceraldehyde-3-P_DHase_2_arc.
Graphical view of domain structure.
PANTHER PTHR10836; GAP_DH; 1.
Pfam PF02800; Gp_dh_C; 1.
PF00044; Gp_dh_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000149; GAP_DH; 1.
ProDom PD007761; GAPDH_like; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR01546; GAPDH-II_archae; 1.
PROSITE PS00071; GAPDH; 1.
BLOCKS Q97BJ8.
Genome annotation databases
GeneID 1440974; -.
GenomeReviews BA000011_GR; TV0457.
KEGG tvo:TVN0458; -.
NMPDR fig|273116.1.peg.458; -.
Phylogenomic databases
HOGENOM Q97BJ8; -.
Genome annotation databases
CMR Q97BJ8; TV0457.
Other
ProtoNet Q97BJ8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Glycolysis; NAD; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   338  338     Glyceraldehyde-3-phosphate dehydrogenase. PRO_0000145738
NP_BIND   11    12  2     NAD (By similarity). 
REGION   138   140  3     Glyceraldehyde 3-phosphate binding (By similarity). 
REGION   192   193  2     Glyceraldehyde 3-phosphate binding (By similarity). 
ACT_SITE   139   139        Nucleophile (By similarity). 
BINDING   109   109        NAD; via amide nitrogen (By similarity). 
BINDING   167   167        NAD (By similarity). 
BINDING   169   169        Glyceraldehyde 3-phosphate (By similarity). 
BINDING   299   299        NAD; via carbonyl oxygen (By similarity). 
Sequence information
Length: 338 AA [This is the length of the unprocessed precursor] Molecular weight: 37374 Da [This is the MW of the unprocessed precursor] CRC64: C9BD53DFD4722F34 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MIRVGINGYG TIGRRVANAV SSQDDMIVVG IVKTKPDYIS EVASRRFKIF VPDSSYMKAF 

        70         80         90        100        110        120 
QDAGIKVEGT LDNLLDDAEI IVDATPEGMG EKNKPLYIKK KAKAIFEGGE EPDVAETSFN 

       130        140        150        160        170        180 
AYSNYNDAIG KSYVRVVSCN TTGLARTLYP IQQAFGVKHV EATLIRRATD QNDSSKGPIN 

       190        200        210        220        230        240 
AVEPSLKIPS HHAPDLKTVM GNIDVNTVAI KVPTTLMHVH VVQVDTEKNA SNDGVLEAWN 

       250        260        270        280        290        300 
NYRRIIHVKK DDGIKSTAQI MDLAREFGRD RSDLYEIAIW EGSVSAKANR ISYIQAVHQE 

       310        320        330 
SDVIPENVDA IRAMFNLADK EKSIEKTDKS LGIEKRVY
Q97BJ8 in FASTA format

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