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UniProtKB/Swiss-Prot entry Q9A7V7


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PH4H_CAUCR
Primary accession number Q9A7V7
Secondary accession numbers None
Integrated into Swiss-Prot on April 16, 2002
Sequence was last modified on June 1, 2001 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 50)
Name and origin of the protein
Protein name Phenylalanine-4-hydroxylase
Synonyms PAH
EC 1.14.16.1
Phe-4-monooxygenase
Gene name
Name: phhA
OrderedLocusNames: CC_1612
From
Caulobacter crescentus (Caulobacter vibrioides) [TaxID: 155892] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales; Caulobacteraceae; Caulobacter.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 19089 / CB15;
DOI=10.1073/pnas.061029298; PubMed=11259647 [NCBI, ExPASy, EBI, Israel, Japan]
Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E., Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R., Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B., DeBoy R.T., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R., Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O., Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M.;
"Complete genome sequence of Caulobacter crescentus.";
Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE005673; AAK23591.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR C87449; C87449.
RefSeq NP_420423.1; -.
3D structure databases
HSSP P30967; 1LTZ. [HSSP ENTRY / PDB]
ModBase Q9A7V7.
Family and domain databases
InterPro IPR001273; Aaa_hydroxylase.
IPR005960; Phe-4-hydroxylase_mono.
Graphical view of domain structure.
Gene3D G3DSA:1.10.800.10; Aaa_hydroxylase; 1.
PANTHER PTHR11473; Aaa_hydroxylase; 1.
Pfam PF00351; Biopterin_H; 1.
Pfam graphical view of domain structure.
PRINTS PR00372; FYWHYDRXLASE.
ProDom PD002559; Aaa_hydroxylase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR01267; Phe4hydrox_mono; 1.
PROSITE PS00367; BIOPTERIN_HYDROXYL; 1.
BLOCKS Q9A7V7.
Genome annotation databases
GeneID 941967; -.
GenomeReviews AE005673_GR; CC_1612.
KEGG ccr:CC_1612; -.
NMPDR fig|190650.1.peg.1603; -.
TIGR CC_1612; -.
Phylogenomic databases
HOGENOM Q9A7V7; -.
Other
ProtoNet Q9A7V7.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Iron; Metal-binding; Monooxygenase; Oxidoreductase; Phenylalanine catabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   294  294     Phenylalanine-4-hydroxylase. PRO_0000205554
METAL   129   129        Iron (Potential). 
METAL   134   134        Iron (Potential). 
METAL   175   175        Iron (Potential). 
Sequence information
Length: 294 AA [This is the length of the unprocessed precursor] Molecular weight: 32761 Da [This is the MW of the unprocessed precursor] CRC64: A623276FD0506720 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSGDGLSNGP PPGARPDWTI DQGWETYTQA EHDVWITLYE RQTDMLHGRA CDEFMRGLDA 

        70         80         90        100        110        120 
LDLHRSGIPD FARINEELKR LTGWTVVAVP GLVPDDVFFD HLANRRFPAG QFIRKPHELD 

       130        140        150        160        170        180 
YLQEPDIFHD VFGHVPMLTD PVFADYMQAY GEGGRRALGL GRLANLARLY WYTVEFGLMN 

       190        200        210        220        230        240 
TPAGLRIYGA GIVSSRTESI FALDDPSPNR IGFDLERVMR TLYRIDDFQQ VYFVIDSIQT 

       250        260        270        280        290 
LQEVTLRDFG AIYERLASVS DIGVAEIVPG DAVLTRGTQA YATAGGRLAG AAAG 

Q9A7V7 in FASTA format

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