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UniProtKB/Swiss-Prot entry Q9BXJ5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name C1QT2_HUMAN
Primary accession number Q9BXJ5
Secondary accession numbers None
Integrated into Swiss-Prot on April 16, 2002
Sequence was last modified on June 1, 2001 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 64)
Name and origin of the protein
Protein name Complement C1q tumor necrosis factor-related protein 2 [Precursor]
Synonyms None
Gene name
Name: C1QTNF2
Synonyms: CTRP2
ORFNames: UNQ6349/PRO21054
From
Homo sapiens (Human) [TaxID: 9606] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [MRNA].
Piddington C.S., Bishop P.;
"Homo sapiens complement-c1q tumor necrosis factor-related protein.";
Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases.
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
DOI=10.1101/gr.1293003; PubMed=12975309 [NCBI, ExPASy, EBI, Israel, Japan]
Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J., Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P., Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E., Heldens S., Huang A., Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D., Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L., Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C., Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J., Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M.;
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.";
Genome Res. 13:2265-2270(2003).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Brain, and Muscle;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF329836; AAK17960.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY358839; AAQ89198.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BC011699; AAH11699.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BC054506; AAH54506.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_114114.2; -.
UniGene Hs.110062
3D structure databases
HSSP Q60994; 1C28. [HSSP ENTRY / PDB]
ModBase Q9BXJ5.
Organism-specific databases
H-InvDB HIX0005376; -.
HGNC HGNC:14325; C1QTNF2.
GenAtlas C1QTNF2.
PharmGKB PA25629; -.
GeneCards Q9BXJ5.
Gene expression databases
ArrayExpress Q9BXJ5; -.
CleanEx HS_C1QTNF2; -.
GermOnline ENSG00000145861; Homo sapiens.
Family and domain databases
InterPro IPR001073; C1q.
IPR008160; Collagen.
IPR008983; Tumour_necrosis_fac-like.
Graphical view of domain structure.
Gene3D G3DSA:2.60.120.40; Tumour_necrosis_fac-like; 1.
Pfam PF00386; C1q; 1.
PF01391; Collagen; 2.
Pfam graphical view of domain structure.
PRINTS PR00007; COMPLEMNTC1Q.
SMART SM00110; C1Q; 1.
SMART graphical view of domain structure.
PROSITE PS50871; C1Q; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q9BXJ5.
Genome annotation databases
Ensembl ENSG00000145861; Homo sapiens. [Contig view]
GeneID 114898; -.
KEGG hsa:114898; -.
Phylogenomic databases
HOGENOM Q9BXJ5; -.
HOVERGEN Q9BXJ5; -.
Other
ProtoNet Q9BXJ5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Collagen; Secreted; Signal.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
SIGNAL   1    15  15     Potential. 
CHAIN   16   285  270     Complement C1q tumor necrosis factor-related protein 2. PRO_0000003530
DOMAIN   40   141  102     Collagen-like. 
DOMAIN   145   285  141     C1q. 
Sequence information
Length: 285 AA [This is the length of the unprocessed precursor] Molecular weight: 29952 Da [This is the MW of the unprocessed precursor] CRC64: 7E31FF9868D4EDFA [This is a checksum on the sequence]
        10         20         30         40         50         60 
MIPWVLLACA LPCAADPLLG AFARRDFRKG SPQLVCSLPG PQGPPGPPGA PGPSGMMGRM 

        70         80         90        100        110        120 
GFPGKDGQDG HDGDRGDSGE EGPPGRTGNR GKPGPKGKAG AIGRAGPRGP KGVNGTPGKH 

       130        140        150        160        170        180 
GTPGKKGPKG KKGEPGLPGP CSCGSGHTKS AFSVAVTKSY PRERLPIKFD KILMNEGGHY 

       190        200        210        220        230        240 
NASSGKFVCG VPGIYYFTYD ITLANKHLAI GLVHNGQYRI RTFDANTGNH DVASGSTILA 

       250        260        270        280 
LKQGDEVWLQ IFYSEQNGLF YDPYWTDSLF TGFLIYADQD DPNEV 

Q9BXJ5 in FASTA format

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