ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q9CQF9


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name PCYOX_MOUSE
Primary accession number Q9CQF9
Secondary accession numbers Q3UHV6 Q69ZW0 Q8BZX1
Integrated into Swiss-Prot on March 29, 2005
Sequence was last modified on June 1, 2001 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 53)
Name and origin of the protein
Protein name Prenylcysteine oxidase [Precursor]
Synonym EC 1.8.3.5
Gene name
Name: Pcyox1
Synonyms: Kiaa0908
From
Mus musculus (Mouse) [TaxID: 10090] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=C57BL/6J;
TISSUE=Amnion, Liver, Lung, and Testis;
DOI=10.1126/science.1112014; PubMed=16141072 [NCBI, ExPASy, EBI, Israel, Japan]
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J., Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
"The transcriptional landscape of the mammalian genome.";
Science 309:1559-1563(2005).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=FVB/N;
TISSUE=Mammary tumor;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 5-505.
TISSUE=Fetal brain;
DOI=10.1093/dnares/11.3.205; PubMed=15368895 [NCBI, ExPASy, EBI, Israel, Japan]
Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Seino S., Nishimura M., Kaisho T., Hoshino K., Kitamura H., Nagase T., Ohara O., Koga H.;
"Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.";
DNA Res. 11:205-218(2004).
[4]
PROTEIN SEQUENCE OF 145-151; 169-193; 292-298; 328-349 AND 421-430, AND MASS SPECTROMETRY.
STRAIN=C57BL/6;
TISSUE=Brain;
Lubec G., Kang S.U.;
Submitted (APR-2007) to UniProtKB.
[5]
GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-196, AND MASS SPECTROMETRY.
TISSUE=Plasma;
DOI=10.1021/pr060186m; PubMed=16944957 [NCBI, ExPASy, EBI, Israel, Japan]
Ghesquiere B., Van Damme J., Martens L., Vandekerckhove J., Gevaert K.;
"Proteome-wide characterization of N-glycosylation events by diagonal chromatography.";
J. Proteome Res. 5:2438-2447(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AK004799; BAB23572.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AK004840; BAB23607.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AK031585; BAC27462.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AK033373; BAC28252.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AK049412; BAC33741.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AK145366; BAE26391.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AK147190; BAE27750.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AK161616; BAE36494.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AK169209; BAE40981.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BC028308; AAH28308.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AK173058; BAD32336.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_080099.1; -.
UniGene Mm.30849
3D structure databases
ModBase Q9CQF9.
Organism-specific databases
MGI MGI:1914131; Pcyox1.
Gene expression databases
ArrayExpress Q9CQF9; -.
CleanEx MM_PCYOX1; -.
GermOnline ENSMUSG00000029998; Mus musculus.
Ontologies
GO
GO:0001735; Molecular function: prenylcysteine oxidase activity (inferred from mutant phenotype from MGI).
GO:0030328; Biological process: prenylcysteine catabolic process (inferred from mutant phenotype from MGI).
QuickGo view.
Family and domain databases
InterPro IPR000759; Adrndx_reductase.
IPR013027; FAD_pyr_nucl-diS_OxRdtase.
IPR010795; Prenylcys_lyase.
IPR017046; Prenylcysteine_Oxase.
Graphical view of domain structure.
Pfam PF07156; Prenylcys_lyase; 1.
PF07992; Pyr_redox_2; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF036292; Prenylcysteine_oxidase; 1.
PRINTS PR00419; ADXRDTASE.
BLOCKS Q9CQF9.
Genome annotation databases
Ensembl ENSMUSG00000029998; Mus musculus. [Contig view]
GeneID 66881; -.
KEGG mmu:66881; -.
Phylogenomic databases
HOGENOM Q9CQF9; -.
HOVERGEN Q9CQF9; -.
Other
SOURCE Pcyox1; Mus musculus.
ROUGE KIAA0908.
ProtoNet Q9CQF9.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Direct protein sequencing; FAD; Glycoprotein; Lysosome; Oxidoreductase; Signal; Ubl conjugation.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
SIGNAL   1    28  28     Potential. 
CHAIN   29   505  477     Prenylcysteine oxidase. PRO_0000023300
CARBOHYD   196   196        N-linked (GlcNAc...). 
CARBOHYD   323   323        N-linked (GlcNAc...) (Potential). 
CARBOHYD   353   353        N-linked (GlcNAc...) (Potential). 
CROSSLNK   162   162        Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) (By similarity). 
CONFLICT   114   114        S -> T (in Ref. 1; BAC28252). 
Sequence information
Length: 505 AA [This is the length of the unprocessed precursor] Molecular weight: 56495 Da [This is the MW of the unprocessed precursor] CRC64: 9169BC4CC7D97561 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MGRFAAALVG SLFWLGLLLC GLGSLASAEP RAPPNRIAIV GAGIGGTSSA YYLRKKFGKD 

        70         80         90        100        110        120 
VKIDVFEREE VGGRLATLKV QGHDYEAGGS VIHPLNLHMK RFVKELGLSS VPASGGLVGV 

       130        140        150        160        170        180 
YNGKSLVFEE SSWFVINVIK LVWRYGFQSL RMHMWVEDLL DKFMRIYRYQ SHDYAFSSVE 

       190        200        210        220        230        240 
KLMHAIGGDD YVRLLNQTLR ENLKKAGFSE TFLNEMIAPV MKVNYGQSTD INAFVGAVSL 

       250        260        270        280        290        300 
TAADSNLWAV EGGNKIVCSG LLQASSSNLI SGSVMSIEEK TRTKQTGNPT KMYEVVYKTG 

       310        320        330        340        350        360 
SETHSDFYDI VLVAAPLNRK MSNITFRNFD PPIEEFNDPY QQLVTTFIKG ELNSTLFSSR 

       370        380        390        400        410        420 
PKDQFGLSAI LVTDDSDMFI NSLSIVASVR QKEGPPPAVD GMHVWKTFSR DILTKEQISK 

       430        440        450        460        470        480 
LFLSYDYAVR KPWLSYPHYE PPQKCPSIIL HDRLYYLNGI EFAASCMEMS AIAGYNAALL 

       490        500 
AYHRWNGNED MIDQDDLYER LKTEL 

Q9CQF9 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by ca flag CBR Canada Mirror sites: Australia  Brazil  China  Korea  Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!