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UniProtKB/Swiss-Prot entry Q9FM01


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name UGDH2_ARATH
Primary accession number Q9FM01
Secondary accession number Q84MD5
Integrated into Swiss-Prot on December 4, 2007
Sequence was last modified on March 1, 2001 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 46)
Name and origin of the protein
Protein name Probable UDP-glucose 6-dehydrogenase 2
Synonyms UDP-Glc dehydrogenase 2
UDP-GlcDH 2
UDPGDH 2
EC 1.1.1.22
Gene name
Name: UGD2
OrderedLocusNames: At5g39320
ORFNames: K3K3.170
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1093/dnares/5.1.41; PubMed=9628582 [NCBI, ExPASy, EBI, Israel, Japan]
Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N., Tabata S.;
"Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence features of the regions of 1,456,315 bp covered by nineteen physically assigned P1 and TAC clones.";
DNA Res. 5:41-54(1998).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AB009054; BAB11006.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AB010694; BAB11006.1; JOINED; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BT006380; AAP21188.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_198748.1; -.
UniGene At.20102
3D structure databases
ModBase Q9FM01.
Organism-specific databases
TAIR At5g39320; -.
Family and domain databases
InterPro IPR016040; NAD(P)-bd.
IPR017476; Nucleotide_sugar_DH.
IPR014027; UDP-Glc/GDP-Man_DHase_C.
IPR014026; UDP-Glc/GDP-Man_DHase_dimer.
IPR014028; UDP-Glc/GDP-Man_DHase_dimer-bd.
IPR001732; UDP-Glc/GDP-Man_DHase_N.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:3.40.50.1870; UDP-Glc/GDP-Man_DH_C; 1.
PANTHER PTHR11374; UDPG_MGDP_DH_Creg; 1.
Pfam PF00984; UDPG_MGDP_dh; 1.
PF03720; UDPG_MGDP_dh_C; 1.
PF03721; UDPG_MGDP_dh_N; 1.
Pfam graphical view of domain structure.
BLOCKS Q9FM01.
Genome annotation databases
GeneID 833928; -.
GenomeReviews BA000015_GR; AT5G39320.
KEGG ath:AT5G39320; -.
NMPDR fig|3702.1.peg.25628; -.
Other
ProtoNet Q9FM01.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase; Phosphoprotein.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   480  480     Probable UDP-glucose 6-dehydrogenase 2. PRO_0000312028
NP_BIND   3    20  18     NAD (By similarity). 
REGION   158   161  4     Substrate binding (By similarity). 
ACT_SITE   272   272        Nucleophile (By similarity). 
BINDING   33    33        NAD (By similarity). 
BINDING   38    38        NAD (By similarity). 
BINDING   90    90        NAD (By similarity). 
BINDING   128   128        NAD; via amide nitrogen (By similarity). 
BINDING   161   161        NAD (By similarity). 
BINDING   216   216        Substrate (By similarity). 
BINDING   269   269        Substrate; via amide nitrogen (By similarity). 
BINDING   275   275        NAD (By similarity). 
BINDING   335   335        Substrate (By similarity). 
BINDING   342   342        NAD (By similarity). 
MOD_RES   393   393        Phosphoserine (By similarity). 
CONFLICT   92    92        Missing (in Ref. 2; AAP21188). 
Sequence information
Length: 480 AA [This is the length of the unprocessed precursor] Molecular weight: 53097 Da [This is the MW of the unprocessed precursor] CRC64: 3FC4FEB2CB647BCB [This is a checksum on the sequence]
        10         20         30         40         50         60 
MVKICCIGAG YVGGPTMAVI ALKCPDIEVA VVDISVPRIN AWNSDQLPIY EPGLDDIVKQ 

        70         80         90        100        110        120 
CRGKNLFFST DVEKHVREAD IVFVSVNTPT KTTGLGAGKA ADLTYWESAA RMIADVSVSD 

       130        140        150        160        170        180 
KIVVEKSTVP VKTAEAIEKI LMHNSKGIKF QILSNPEFLA EGTAIADLFN PDRVLIGGRE 

       190        200        210        220        230        240 
TPEGFKAVQT LKEVYANWVP EGQIITTNLW SAELSKLAAN AFLAQRISSV NAMSALCEST 

       250        260        270        280        290        300 
GADVTQVSYA VGTDSRIGSK FLNASVGFGG SCFQKDILNL VYICQCNGLP EVAEYWKQVI 

       310        320        330        340        350        360 
KINDYQKNRF VNRIVSSMFN TVSNKKVAIL GFAFKKDTGD TRETPAIDVC KGLLGDKAQI 

       370        380        390        400        410        420 
SIYDPQVTEE QIQRDLSMKK FDWDHPLHLQ PMSPTTVKQV SVTWDAYEAT KDAHAVCVLT 

       430        440        450        460        470        480 
EWDEFKSLDY QKIFDNMQKP AFIFDGRNIM NVNKLREIGF IVYSIGKPLD PWLKDMPAFV 

Q9FM01 in FASTA format

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