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UniProtKB/Swiss-Prot entry Q9HDX2


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name YKN3_SCHPO
Primary accession number Q9HDX2
Secondary accession numbers None
Integrated into Swiss-Prot on February 5, 2008
Sequence was last modified on March 1, 2001 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 38)
Name and origin of the protein
Protein name Uncharacterized lactate 2-monooxygenase PB1A11.03
Synonym EC 1.13.12.4
Gene name
ORFNames: SPAPB1A11.03
From
Schizosaccharomyces pombe (Fission yeast) [TaxID: 4896] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 38366 / 972;
DOI=10.1038/nature724; PubMed=11859360 [NCBI, ExPASy, EBI, Israel, Japan]
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
"The genome sequence of Schizosaccharomyces pombe.";
Nature 415:871-880(2002).
[2]
SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
DOI=10.1038/nbt1222; PubMed=16823372 [NCBI, ExPASy, EBI, Israel, Japan]
Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.;
"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.";
Nat. Biotechnol. 24:841-847(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CU329670; CAC19728.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_593999.1; -.
3D structure databases
HSSP P05414; 1GOX. [HSSP ENTRY / SWISS-3DIMAGE / PDB]
ModBase Q9HDX2.
Organism-specific databases
GeneDB_Spombe SPAPB1A11.03; -.
Gene expression databases
ArrayExpress Q9HDX2; -.
Ontologies
GO
GO:0005829; Cellular component: cytosol (inferred from direct assay from GeneDB_SPombe).
GO:0005634; Cellular component: nucleus (inferred from direct assay from GeneDB_SPombe).
QuickGo view.
Family and domain databases
InterPro IPR013785; Aldolase_TIM.
IPR012133; Alpha_OHA_DHase_FMN.
IPR008259; FMN_hydac_DHase_AS.
IPR000262; FMN_OHA_DHase.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF01070; FMN_dh; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000138; Al-hdrx_acd_dh; 1.
PROSITE PS00557; FMN_HYDROXY_ACID_DH_1; 1.
PS51349; FMN_HYDROXY_ACID_DH_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q9HDX2.
Genome annotation databases
GeneID 2543401; -.
KEGG spo:SPAPB1A11.03; -.
NMPDR fig|4896.1.peg.3969; -.
Other
ProtoNet Q9HDX2.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Flavoprotein; FMN; Monooxygenase; Nucleus; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   407  407     Uncharacterized lactate 2-monooxygenase PB1A11.03. PRO_0000316582
DOMAIN   28   406  379     FMN hydroxy acid dehydrogenase. 
NP_BIND   332   356  25     FMN (By similarity). 
ACT_SITE   301   301        Proton acceptor (By similarity). 
BINDING   54    54        Substrate (Potential). 
BINDING   136   136        FMN (By similarity). 
BINDING   158   158        FMN (By similarity). 
BINDING   160   160        Substrate (By similarity). 
BINDING   188   188        FMN (By similarity). 
BINDING   197   197        Substrate (By similarity). 
BINDING   277   277        FMN (By similarity). 
BINDING   304   304        Substrate (Potential). 
Sequence information
Length: 407 AA [This is the length of the unprocessed precursor] Molecular weight: 45311 Da [This is the MW of the unprocessed precursor] CRC64: B0039309D1093CA4 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MFRNYNWFDA KEPISYESEI YAKGLKFQRP QITVDGRHWE QLAVERMTKD AAGYVYGCAG 

        70         80         90        100        110        120 
KRETYDKNME SFKKWSIIPN RLIKSGFPDL STTVFGQKYP FPIALAPVGV QKIFNPEGES 

       130        140        150        160        170        180 
GSCAAATREH IPYIISTASA TSFEDIEKAS GPGERWYQLY WPSNDHQDIT ISLLNRAKKT 

       190        200        210        220        230        240 
GCRVLIVTLD TFILGWRPSD MDNGYDPFLN PDSIGVEHGF SDPVFRKQFK EKHGVEVEEN 

       250        260        270        280        290        300 
MLEAAKEFAG IVFPGISHDW EDLKFLRKHW DGPIVLKGIM NVPDAKKAVE YGMQGIVVSN 

       310        320        330        340        350        360 
HGGRQQDGGV ASLTMLPKIV DAVGDKLDVL FDSGVRSGAD IAKALALGAK MVLIGRPYVY 

       370        380        390        400 
GLALEGSSGV SHVIRCLLGD LELTLHLSGI VSVKPKDLNR DVLYKEE 

Q9HDX2 in FASTA format

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