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UniProtKB/Swiss-Prot entry Q9HJ69

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G3P_THEAC
Primary accession number Q9HJ69
Secondary accession numbers None
Integrated into Swiss-Prot on May 27, 2002
Sequence was last modified on March 1, 2001 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 47)
Name and origin of the protein
Protein name Glyceraldehyde-3-phosphate dehydrogenase
Synonyms GAPDH
EC 1.2.1.59
NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase
Gene name
Name: gap
OrderedLocusNames: Ta1103
From
Thermoplasma acidophilum [TaxID: 2303] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Thermoplasmata; Thermoplasmatales; Thermoplasmataceae; Thermoplasma.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 25905 / AMRC-C165 / DSM 1728 / IFO 15155 / JCM 9062;
DOI=10.1038/35035069; PubMed=11029001 [NCBI, ExPASy, EBI, Israel, Japan]
Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C., Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W.;
"The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum.";
Nature 407:508-513(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL445066; CAC12230.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_394562.1; -.
3D structure databases
HSSP P10618; 1CF2. [HSSP ENTRY / PDB]
ModBase Q9HJ69.
Enzyme and pathway databases
BioCyc TACI273075:TA1103-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004365; Molecular function: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity (inferred from electronic annotation from HAMAP).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00559; -; 1.
PBIL [Tree]
InterPro IPR000173; GlycerAld_3-P_DHase.
IPR006436; Glyceraldehyde-3-P_DHase_2_arc.
Graphical view of domain structure.
PANTHER PTHR10836; GAP_DH; 1.
Pfam PF02800; Gp_dh_C; 1.
PF00044; Gp_dh_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000149; GAP_DH; 1.
ProDom PD007761; GAPDH_like; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR01546; GAPDH-II_archae; 1.
PROSITE PS00071; GAPDH; 1.
BLOCKS Q9HJ69.
Genome annotation databases
GeneID 1456612; -.
GenomeReviews AL139299_GR; Ta1103.
KEGG tac:Ta1103; -.
NMPDR fig|273075.1.peg.1084; -.
Phylogenomic databases
HOGENOM Q9HJ69; -.
Genome annotation databases
CMR Q9HJ69; Ta1103.
Other
ProtoNet Q9HJ69.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Glycolysis; NAD; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   338  338     Glyceraldehyde-3-phosphate dehydrogenase. PRO_0000145737
NP_BIND   11    12  2     NAD (By similarity). 
REGION   138   140  3     Glyceraldehyde 3-phosphate binding (By similarity). 
REGION   192   193  2     Glyceraldehyde 3-phosphate binding (By similarity). 
ACT_SITE   139   139        Nucleophile (By similarity). 
BINDING   109   109        NAD; via amide nitrogen (By similarity). 
BINDING   167   167        NAD (By similarity). 
BINDING   169   169        Glyceraldehyde 3-phosphate (By similarity). 
BINDING   299   299        NAD; via carbonyl oxygen (By similarity). 
Sequence information
Length: 338 AA [This is the length of the unprocessed precursor] Molecular weight: 37784 Da [This is the MW of the unprocessed precursor] CRC64: 8CEA4DF107909AE5 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MIRVGINGYG TIGRRVARAV SLQDDMIVTG IVKTKPDYVS MVASRDFKIF VPDKSYEKAF 

        70         80         90        100        110        120 
QDAGIKVEGT VENLIDDSEI IVDATPEGQG EKNKDLYVKR RIKAIFEGGE EPEIAQASFN 

       130        140        150        160        170        180 
AYSNFEEARS KDYVRVVSCN TTALARTLHP LRERFGIRYV DATIVRRATD PNDSKKGPIN 

       190        200        210        220        230        240 
AVEPSLSIPS HHAPDLRTVM SGLNVSTIAI KAPTTLMHVH AVRVELEKDA SKNDVIEAWR 

       250        260        270        280        290        300 
SYRRIMEIGK NSGITSTGQM MDLAREFGRD RSDLYEIAVW SQSVSVQGNH VSYIQAVHQE 

       310        320        330 
SDVVPENVDA IRSMFDIADR DRSVSMTDSK LKIEKRVF
Q9HJ69 in FASTA format

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