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UniProtKB/Swiss-Prot entry Q9JUD9

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CYSI_NEIMA
Primary accession number Q9JUD9
Secondary accession number A1IRY7
Integrated into Swiss-Prot on September 13, 2005
Sequence was last modified on October 1, 2000 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 37)
Name and origin of the protein
Protein name Sulfite reductase [NADPH] hemoprotein beta-component
Synonyms SIR-HP
SIRHP
EC 1.8.1.2
Gene name
Name: cysI
OrderedLocusNames: NMA1362
From
Neisseria meningitidis serogroup A [TaxID: 65699] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae; Neisseria.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Z2491 / Serogroup A / Serotype 4A;
DOI=10.1038/35006655; PubMed=10761919 [NCBI, ExPASy, EBI, Israel, Japan]
Parkhill J., Achtman M., James K.D., Bentley S.D., Churcher C.M., Klee S.R., Morelli G., Basham D., Brown D., Chillingworth T., Davies R.M., Davis P., Devlin K., Feltwell T., Hamlin N., Holroyd S., Jagels K., Leather S., Moule S., Mungall K.L., Quail M.A., Rajandream M.A., Rutherford K.M., Simmonds M., Skelton J., Whitehead S., Spratt B.G., Barrell B.G.;
"Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491.";
Nature 404:502-506(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL157959; CAM08535.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR D81905; D81905.
3D structure databases
HSSP P17846; 7GEP. [HSSP ENTRY / PDB]
ModBase Q9JUD9.
Enzyme and pathway databases
BioCyc NMEN122587:NMA1362-MON; -.
Ontologies
GO
GO:0004783; Molecular function: sulfite reductase (NADPH) activity (inferred from electronic annotation from HAMAP).
GO:0000103; Biological process: sulfate assimilation (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01540; -; 1.
PBIL [Tree]
InterPro IPR011786; CysI.
IPR006066; Nir_Si_BS.
IPR006067; Nir_Sir_4Fe4S.
IPR005117; NiRdtase/SiRdtase_haem-b_fer.
Graphical view of domain structure.
Pfam PF01077; NIR_SIR; 1.
PF03460; NIR_SIR_ferr; 2.
Pfam graphical view of domain structure.
PRINTS PR00397; SIROHAEM.
TIGRFAMs TIGR02041; CysI; 1.
PROSITE PS00365; NIR_SIR; 1.
BLOCKS Q9JUD9.
Genome annotation databases
GenomeReviews AL157959_GR; NMA1362.
KEGG nma:NMA1362; -.
Phylogenomic databases
HOGENOM Q9JUD9; -.
Genome annotation databases
CMR Q9JUD9; NMA1362.
Other
ProtoNet Q9JUD9.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
4Fe-4S; Amino-acid biosynthesis; Complete proteome; Cysteine biosynthesis; Heme; Iron; Iron-sulfur; Metal-binding; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   589  589     Sulfite reductase [NADPH] hemoprotein beta-component. PRO_0000199901
METAL   443   443        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   449   449        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   488   488        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   492   492        Iron (siroheme axial ligand) (By similarity). 
METAL   492   492        Iron-sulfur (4Fe-4S) (By similarity). 
Sequence information
Length: 589 AA [This is the length of the unprocessed precursor] Molecular weight: 65851 Da [This is the MW of the unprocessed precursor] CRC64: 1F1B039B15128DCF [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTVQTKTKGL AWQEKPLSDN ERLKTESNFL RGTILDDLKD PLTGGFKGDN FQLIRFHGMY 

        70         80         90        100        110        120 
EQDDRDIRAE RAEAKLEPLK FMLLRCRLPG GIIKPSQWIE LDKFARENSH YRSIRLTNRQ 

       130        140        150        160        170        180 
TFQFHGVPKA KLQTMHRLLH KLGLDSIATA ADMNRNVLCT SNPIESELHR QAYEYAKKIS 

       190        200        210        220        230        240 
EHLLPRTRGY LDVWVDGKKV QSSDDFLQED EPILGKTYLP RKFKTAVVIP PLNDVDCYGN 

       250        260        270        280        290        300 
DLDFVAISDG NGQLAGFNVL AGGGLSMEHG NTKTYPNISL ELGFVPPEHA LKAAEAVVTT 

       310        320        330        340        350        360 
QRDFGNRSDR KNARTRYTIQ NMGLDNFRAE VERRMGMPFE PIRPFKFTGR GDRIGWVKGI 

       370        380        390        400        410        420 
DGNWHLTLFI ESGRLVDEGG KQLLTGVLEI AKIHKGDFRI TANQNLIVAN VPEGGKARIE 

       430        440        450        460        470        480 
QLARSYGLIH DGVSKLRENA MSCVSFPTCP LAMAEAERVL PDFIGELDKI MAKHGTSDDY 

       490        500        510        520        530        540 
IVTRITGCPN GCGRAMLAEI GLVGKAVGRY NLHIGGDREG VRIPRLYKEN ITLPEILAEL 

       550        560        570        580 
DDLIGKWAAE RNIGEGFGDF AIRTGIVKPV LNAPVDFWDA SKAVAIARA
Q9JUD9 in FASTA format

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