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UniProtKB/Swiss-Prot entry Q9LRR9


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GOX2_ARATH
Primary accession number Q9LRR9
Secondary accession numbers Q8VZA4 Q944K6
Integrated into Swiss-Prot on February 21, 2001
Sequence was last modified on October 1, 2000 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 57)
Name and origin of the protein
Protein name Probable peroxisomal (S)-2-hydroxy-acid oxidase 2
Synonyms EC 1.1.3.15
Glycolate oxidase 2
GOX 2
Short chain alpha-hydroxy acid oxidase 2
Gene name
OrderedLocusNames: At3g14420
ORFNames: MAO2.2
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1093/dnares/7.2.131; PubMed=10819329 [NCBI, ExPASy, EBI, Israel, Japan]
Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
"Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones.";
DNA Res. 7:131-135(2000).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AB028617; BAB01334.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY053412; AAK96642.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AF428396; AAL16164.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AF428328; AAL16258.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY065122; AAL38298.1; ALT_INIT; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY074830; AAL69528.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY081566; AAM10128.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_188060.1; -.
NP_850584.1; -.
UniGene At.21768
3D structure databases
HSSP P05414; 1AL8. [HSSP ENTRY / SWISS-3DIMAGE / PDB]
SMR Q9LRR9; 1-359.
ModBase Q9LRR9.
Organism-specific databases
TAIR At3g14420; -.
Ontologies
GO
GO:0003973; Molecular function: (S)-2-hydroxy-acid oxidase activity (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR013785; Aldolase_TIM.
IPR012133; Alpha_OHA_DHase_FMN.
IPR008259; FMN_hydac_DHase_AS.
IPR000262; FMN_OHA_DHase.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF01070; FMN_dh; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000138; Al-hdrx_acd_dh; 1.
PROSITE PS00557; FMN_HYDROXY_ACID_DH_1; 1.
PS51349; FMN_HYDROXY_ACID_DH_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q9LRR9.
Proteomic databases
ProMEX Q9LRR9; -.
Genome annotation databases
GeneID 820665; -.
GenomeReviews BA000014_GR; AT3G14420.
NMPDR fig|3702.1.peg.13579; -.
Other
ProtoNet Q9LRR9.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Alternative splicing; Complete proteome; Flavoprotein; FMN; Glycolate pathway; Oxidoreductase; Peroxisome; Photorespiration.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   367  367     Probable peroxisomal (S)-2-hydroxy-acid oxidase 2. PRO_0000206324
DOMAIN   1   359  359     FMN hydroxy acid dehydrogenase. 
NP_BIND   285   309  25     FMN (By similarity). 
MOTIF   365   367  3     Microbody targeting signal (Potential). 
ACT_SITE   254   254        Proton acceptor (By similarity). 
BINDING   24    24        Substrate (Potential). 
BINDING   106   106        FMN (By similarity). 
BINDING   127   127        FMN (By similarity). 
BINDING   129   129        Substrate (By similarity). 
BINDING   155   155        FMN (By similarity). 
BINDING   164   164        Substrate (By similarity). 
BINDING   230   230        FMN (By similarity). 
BINDING   257   257        Substrate (Potential). 
CONFLICT   55    55        V -> A (in Ref. 2; AAL16258). 
CONFLICT   363   363        P -> L (in Ref. 2; AAL38298/AAM10128). 
Sequence information
Length: 367 AA [This is the length of the unprocessed precursor] Molecular weight: 40341 Da [This is the MW of the unprocessed precursor] CRC64: B107AD7AC983A04C [This is a checksum on the sequence]
        10         20         30         40         50         60 
MEITNVTEYD AIAKQKLPKM VYDYYASGAE DQWTLQENRN AFARILFRPR ILIDVSKIDM 

        70         80         90        100        110        120 
TTTVLGFKIS MPIMVAPTAM QKMAHPDGEY ATARAASAAG TIMTLSSWAT SSVEEVASTG 

       130        140        150        160        170        180 
PGIRFFQLYV YKNRNVVEQL VRRAERAGFK AIALTVDTPR LGRRESDIKN RFTLPPNLTL 

       190        200        210        220        230        240 
KNFEGLDLGK MDEANDSGLA SYVAGQIDRT LSWKDVQWLQ TITKLPILVK GVLTGEDARI 

       250        260        270        280        290        300 
AIQAGAAGII VSNHGARQLD YVPATISALE EVVKATQGRI PVFLDGGVRR GTDVFKALAL 

       310        320        330        340        350        360 
GASGIFIGRP VVFSLAAEGE AGVRKVLQML RDEFELTMAL SGCRSLKEIS RNHITTEWDT 


PRPSARL 

Q9LRR9 in FASTA format

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