[1]	NUCLEOTIDE SEQUENCE [MRNA]. DOI=10.1016/S0168-9452(01)00332-6; PubMed=11297793 [NCBI, ExPASy, EBI, Israel, Japan] Kwon S.-I., An C.-S.; "Molecular cloning, characterization and expression analysis of a catalase cDNA from hot pepper (Capsicum annuum L.)."; Plant Sci. 160:961-969(2001).

Comments

FUNCTION: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
CATALYTIC ACTIVITY: 2 H₂O₂ = O₂ + 2 H₂O.
COFACTOR: Heme group.
SUBUNIT: Homotetramer (By similarity).
SUBCELLULAR LOCATION: Peroxisome (By similarity).
TISSUE SPECIFICITY: In stems, leaves, roots and developing fruits.
INDUCTION: In roots, by aluminum and salt. Expressed with a circadian rhythm reaching a maximum at late in the dark period or early in the light period.
SIMILARITY: Belongs to the catalase family.

Copyright

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Cross-references

Sequence databases

EMBL

AF227952; AAF34718.1; -; mRNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

JE0126; JE0126.

3D structure databases

HSSP

P46206; 1M7S. [HSSP ENTRY / PDB]

ModBase

Q9M5L6.

Family and domain databases

InterPro

IPR002226; Catalase.
IPR011614; Catalase_N.
Graphical view of domain structure.

Gene3D

G3DSA:2.40.180.10; Catalase_N; 1.

PANTHER

PTHR11465; Catalase; 1.

Pfam

PF00199; Catalase; 1.
Pfam graphical view of domain structure.

PRINTS

PR00067; CATALASE.

ProDom

PD000510; Catalase; 1.
[Domain structure / List of seq. sharing at least 1 domain]

PROSITE

PS00437; CATALASE_1; 1.
PS00438; CATALASE_2; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Heme; Hydrogen peroxide; Iron; Metal-binding; Oxidoreductase; Peroxidase; Peroxisome.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 492`	`492`	`Catalase.`	`PRO_0000084934`
`ACT_SITE`	`65 65`		`By similarity.`
`ACT_SITE`	`138 138`		`By similarity.`
`METAL`	`348 348`		`Iron (heme axial ligand) (By similarity).`

Sequence information

Length: 492 AA [This is the length of the unprocessed precursor]

Molecular weight: 56480 Da [This is the MW of the unprocessed precursor]

CRC64: 5D987B637FCDD4E7 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MDLSKYRPSS AYDSPFLTTN AGGPVYNNVS SLTVGPRGPV LLEDYHLIEK LATFVRERIP 

        70         80         90        100        110        120 
ERVVHARGAS AKGFFEVTHD ISHLTCADFL RAPGVQTPVI CRFSTVVHER GSPESIRDIR 

       130        140        150        160        170        180 
GFAVKFYTRE GNFDLVGNNV PVFFNRDAKS FPDTIRALKP NPKSHIQENW RILDFFSFLP 

       190        200        210        220        230        240 
ESLHTFAFFY DDVCLPTDYR HMEGFGVHAY QLINKAGKAH YVKFHWKPTC GVKSMTEEEA 

       250        260        270        280        290        300 
IRVGGTNHSH ATKDLYDSIA AGNYPEWKLF IQIMNPEDVD KFDFDPLDVT KTWPEDILPL 

       310        320        330        340        350        360 
MPVGRLVLNR NIDNFFAENE QLAFNPGHIV PGVYYSEDKL LQTRIFAYAD TQRHRIGPNY 

       370        380        390        400        410        420 
MQLPVNAPKC AHHNNHRDGA MNFMHRDEEV DYLPSRFDPC RPAEQYPIPS CVLTGRREKC 

       430        440        450        460        470        480 
VIPKENNFKQ AGERYRSWAP DRQDRYINKW VESLSDPRAT HEIRSIWISY LSQADKSCGQ 

       490 
KVASRLTVKP TM

Q9M5L6 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools