ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q9UTJ7


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name DHSA_SCHPO
Primary accession number Q9UTJ7
Secondary accession number P78912
Integrated into Swiss-Prot on May 23, 2003
Sequence was last modified on May 1, 2000 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 59)
Name and origin of the protein
Protein name Probable succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial [Precursor]
Synonyms EC 1.3.5.1
Flavoprotein subunit of complex II
FP
Gene name
Name: sdh1
ORFNames: SPAC1556.02c
From
Schizosaccharomyces pombe (Fission yeast) [TaxID: 4896] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 38366 / 972;
DOI=10.1038/nature724; PubMed=11859360 [NCBI, ExPASy, EBI, Israel, Japan]
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
"The genome sequence of Schizosaccharomyces pombe.";
Nature 415:871-880(2002).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 155-641.
STRAIN=PR745;
DOI=10.1093/dnares/4.6.363; PubMed=9501991 [NCBI, ExPASy, EBI, Israel, Japan]
Yoshioka S., Kato K., Nakai K., Okayama H., Nojima H.;
"Identification of open reading frames in Schizosaccharomyces pombe cDNAs.";
DNA Res. 4:363-369(1997).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CU329670; CAB61213.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
D89263; BAA13924.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T50081; T50081.
RefSeq NP_594319.1; -.
3D structure databases
HSSP P10444; 1NEK. [HSSP ENTRY / PDB]
ModBase Q9UTJ7.
Enzyme and pathway databases
BioCyc SPOM-XXX-01:SPOM-XXX-01-002428-MON; -.
Organism-specific databases
GeneDB_Spombe SPAC1556.02c; -.
Gene expression databases
ArrayExpress Q9UTJ7; -.
Ontologies
GO
GO:0005739; Cellular component: mitochondrion (inferred from direct assay from GeneDB_SPombe).
GO:0006105; Biological process: succinate metabolic process (inferred by curator from GeneDB_SPombe).
QuickGo view.
Family and domain databases
InterPro IPR003953; FAD_bind2_N.
IPR013027; FAD_pyr_nucl-diS_OxRdtase.
IPR003952; FRD_SDH_FAD_BS.
IPR004112; Fum_Rdtase/Succ_DHase_flav_C.
IPR001100; Pyr_nuc-diS_OxRdtase.
IPR011281; Succ_DHase_flav_su_fwd.
IPR014006; Succ_Dhase_frdA_Gneg.
Graphical view of domain structure.
Pfam PF00890; FAD_binding_2; 1.
PF02910; Succ_DH_flav_C; 1.
Pfam graphical view of domain structure.
PRINTS PR00368; FADPNR.
PR00411; PNDRDTASEI.
TIGRFAMs TIGR01816; sdhA_forward; 1.
TIGR01812; sdhA_frdA_Gneg; 1.
PROSITE PS00504; FRD_SDH_FAD_BINDING; 1.
BLOCKS Q9UTJ7.
Genome annotation databases
GeneID 2541690; -.
KEGG spo:SPAC1556.02c; -.
NMPDR fig|4896.1.peg.4289; -.
Other
ProtoNet Q9UTJ7.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Electron transport; FAD; Flavoprotein; Membrane; Mitochondrion; Mitochondrion inner membrane; Oxidoreductase; Transit peptide; Transport; Tricarboxylic acid cycle.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
TRANSIT   1     ?        Mitochondrion (Potential). 
CHAIN   ?   641        Probable succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial. PRO_0000010341
NP_BIND   84    99  16     FAD (By similarity). 
ACT_SITE   333   333        Proton acceptor (By similarity). 
BINDING   289   289        Substrate (By similarity). 
BINDING   301   301        Substrate (By similarity). 
BINDING   400   400        Substrate (By similarity). 
BINDING   445   445        Substrate (By similarity). 
MOD_RES   92    92        Tele-8alpha-FAD histidine (By similarity). 
CONFLICT   214   214        A -> G (in Ref. 2; BAA13924). 
CONFLICT   218   218        I -> L (in Ref. 2; BAA13924). 
Sequence information
Length: 641 AA [This is the length of the unprocessed precursor] Molecular weight: 70466 Da [This is the MW of the unprocessed precursor] CRC64: 5E5FCD857C372199 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MLRFRKVAPS LKNGGNLKLF STSSTLKKIA SSQPLRAKQV STSESVKYPV IDHTYDAIVV 

        70         80         90        100        110        120 
GAGGAGLRAT FGLAEAGFNT ACITKLFPTR SHTVAAQGGI NAALGNMTKD DWRWHFYDTV 

       130        140        150        160        170        180 
KGSDWLGDQD AIHYMTKEAP KAVLELEHFG VPFSRTKEGK IYQRAFGGQS LEYGKGGQAY 

       190        200        210        220        230        240 
RCAAVADRTG HSILHTLYGQ SLKHNTNFFI EYFAMDLIME GGECRGVIAM NLEDGSIHRF 

       250        260        270        280        290        300 
RAHKTILATG GYGRAYFSCT SAHTCTGDGN AMVSRAGLPL QDLEFVQFHP TGIYGAGCLI 

       310        320        330        340        350        360 
TEGCRGEGGY LLNSKGERFM ERYAPTAKDL ASRDVVSRAM TVEIREGRGV GPEKDHCYLQ 

       370        380        390        400        410        420 
LSHLPAEILK ERLPGISETA AIFAGVDVTK EPIPVLPTVH YNMGGIPTRF TGEVLTIDEN 

       430        440        450        460        470        480 
GKDKIVPGLY AAGEAACVSV HGGNRLGANS LLDIVVFGRA CALHIKDTLE PNTPHKPLAA 

       490        500        510        520        530        540 
DAGLDSLKFL DQIRTSQGPK HTSEIRLDMQ KTMQRDVSVF RMEETLQEGV KNIARVDGTY 

       550        560        570        580        590        600 
KDIGIRDRGL IWNTDLVEAL ELRNLLTCAV QTANAALNRK ESRGAHARED YPERDDKNWI 

       610        620        630        640 
KHTLTWQHKT GDPVTLKYRA VTRTTMDENE VKPVPPFKRV Y 

Q9UTJ7 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by ca flag CBR Canada Mirror sites: Australia  Brazil  China  Korea  Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!