ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q9UUH4


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name ERG25_SCHPO
Primary accession number Q9UUH4
Secondary accession numbers None
Integrated into Swiss-Prot on February 22, 2003
Sequence was last modified on May 1, 2000 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 42)
Name and origin of the protein
Protein name C-4 methylsterol oxidase
Synonyms EC 1.14.13.72
Methylsterol monooxygenase
Gene name
Name: erg25
ORFNames: SPAC630.08c
From
Schizosaccharomyces pombe (Fission yeast) [TaxID: 4896] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 38366 / 972;
DOI=10.1038/nature724; PubMed=11859360 [NCBI, ExPASy, EBI, Israel, Japan]
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
"The genome sequence of Schizosaccharomyces pombe.";
Nature 415:871-880(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CU329670; CAB52730.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T38986; T38986.
RefSeq NP_592903.1; -.
3D structure databases
ModBase Q9UUH4.
Enzyme and pathway databases
BioCyc SPOM-XXX-01:SPOM-XXX-01-000634-MON; -.
Organism-specific databases
GeneDB_Spombe SPAC630.08c; -.
Gene expression databases
ArrayExpress Q9UUH4; -.
Ontologies
GO
GO:0005783; Cellular component: endoplasmic reticulum (inferred from direct assay from GeneDB_SPombe).
QuickGo view.
Family and domain databases
InterPro IPR006088; Sterol_desatur.
Graphical view of domain structure.
Pfam PF01598; Sterol_desat; 1.
Pfam graphical view of domain structure.
BLOCKS Q9UUH4.
Genome annotation databases
GeneID 2543373; -.
KEGG spo:SPAC630.08c; -.
NMPDR fig|4896.1.peg.2873; -.
Other
ProtoNet Q9UUH4.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Endoplasmic reticulum; Iron; Lipid synthesis; Membrane; NAD; Oxidoreductase; Steroid biosynthesis; Sterol biosynthesis; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   300  300     C-4 methylsterol oxidase. PRO_0000117038
TRANSMEM   186   206  21     Potential. 
MOTIF   154   158  5     Histidine box-1. 
MOTIF   167   171  5     Histidine box-2. 
MOTIF   251   257  7     Histidine box-3. 
Sequence information
Length: 300 AA [This is the length of the unprocessed precursor] Molecular weight: 35803 Da [This is the MW of the unprocessed precursor] CRC64: AA8C2603D35DF331 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MNTTSEVIVG TGFQAIRQQL AQMHPELNFV EQLWLAYYKW FDNDVVATGL MSFLLHELIY 

        70         80         90        100        110        120 
FGRCIPWMII DAMPYFRRWK IQPKKVPTLA EQWECTRLVL LSHFTVELPQ IWLFDPMCAT 

       130        140        150        160        170        180 
FGLSTSVPFP PVTKMIWQIT LFFFLEDTWH YWAHRLFHYG IFYRFIHKVH HRYSAPFGLS 

       190        200        210        220        230        240 
AEYAHPLEII LLGAGTVFVP LMWCYFTHDL HLVTMYIWIT LRLFQAVDSH AGYDFPWSLN 

       250        260        270        280        290        300 
KFLPIWAGAD HHDYHHMAFK DNFSSSFRWW DAVLKTDQNY HQFKARRLAA KYEAESKKAK 

Q9UUH4 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by ca flag CBR Canada Mirror sites: Australia  Brazil  China  Korea  Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!