ID   PORC_PYRAB              Reviewed;         185 AA.
AC   Q9UYY9;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   04-NOV-2008, entry version 44.
DE   RecName: Full=Pyruvate/ketoisovalerate oxidoreductases common subunit gamma;
DE   Includes:
DE     RecName: Full=Pyruvate synthase subunit porC;
DE              EC=1.2.7.1;
DE     AltName: Full=Pyruvate oxidoreductase gamma chain;
DE              Short=POR;
DE     AltName: Full=Pyruvic-ferredoxin oxidoreductase subunit gamma;
DE   Includes:
DE     RecName: Full=Ketoisovalerate oxidoreductase subunit vorC;
DE              Short=VOR;
DE              EC=1.2.7.7;
DE     AltName: Full=2-oxoisovalerate oxidoreductase gamma chain;
DE     AltName: Full=2-oxoisovalerate ferredoxin reductase subunit gamma;
GN   Name=porG; OrderedLocusNames=PYRAB13680; ORFNames=PAB1470;
OS   Pyrococcus abyssi.
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=29292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GE5 / Orsay;
RX   MEDLINE=22511545; PubMed=12622808;
RX   DOI=10.1046/j.1365-2958.2003.03381.x;
RA   Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O.,
RA   Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C.,
RA   Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P.;
RT   "An integrated analysis of the genome of the hyperthermophilic
RT   archaeon Pyrococcus abyssi.";
RL   Mol. Microbiol. 47:1495-1512(2003).
CC   -!- CATALYTIC ACTIVITY: Pyruvate + CoA + 2 oxidized ferredoxin =
CC       acetyl-CoA + CO(2) + 2 reduced ferredoxin + 2 H(+).
CC   -!- CATALYTIC ACTIVITY: 3-methyl-2-oxobutanoate + CoA + 2 oxidized
CC       ferredoxin = S-(2-methylpropanoyl)-CoA + CO(2) + 2 reduced
CC       ferredoxin + H(+).
CC   -!- SUBUNIT: Heterotetramer of one alpha, one beta, one delta and one
CC       gamma chain.
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DR   EMBL; AJ248287; CAB50273.1; -; Genomic_DNA.
DR   PIR; D75047; D75047.
DR   RefSeq; NP_127043.1; -.
DR   GeneID; 1496757; -.
DR   GenomeReviews; AL096836_GR; PYRAB13680.
DR   KEGG; pab:PAB1470; -.
DR   NMPDR; fig|272844.1.peg.1450; -.
DR   HOGENOM; Q9UYY9; -.
DR   BioCyc; PABY272844:PAB1470-MON; -.
DR   GO; GO:0043807; F:3-methyl-2-oxobutanoate dehydrogenase (ferr...; IEA:EC.
DR   GO; GO:0019164; F:pyruvate synthase activity; IEA:EC.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR011894; PorC_KorC.
DR   InterPro; IPR002869; Pyrv_Fd/Flavodoxin_OxRdtase.
DR   Gene3D; G3DSA:3.40.920.10; Pyrv_Fd/Flavodoxin_OxRdtase; 1.
DR   Pfam; PF01558; POR; 1.
DR   TIGRFAMs; TIGR02175; PorC_KorC; 1.
PE   4: Predicted;
KW   Complete proteome; Oxidoreductase.
FT   CHAIN         1    185       Pyruvate/ketoisovalerate oxidoreductases
FT                                common subunit gamma.
FT                                /FTId=PRO_0000099913.
SQ   SEQUENCE   185 AA;  20023 MW;  2387E6FE6C6A27EC CRC64;
     MIEIRFHGRG GQGAVTAANI LAEAAFIEGK YVQAFPFFGV ERRGAPVTAF TRIDEKPIRI
     KTQIYEPDVV VVLDPSLLET VDVTAGLKED GIVIVNTEKS KEEVLEKLKR KPKKLALVDA
     TTIALETLGL PITNTAILGA VAKATGLVKI ESVETAIKDT FSGELGEKNA KAAREAFEKT
     QIFEV
//