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UniProtKB/Swiss-Prot entry Q9ZPX5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DHSA2_ARATH
Primary accession number Q9ZPX5
Secondary accession numbers None
Integrated into Swiss-Prot on July 25, 2006
Sequence was last modified on May 1, 1999 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 49)
Name and origin of the protein
Protein name Succinate dehydrogenase [ubiquinone] flavoprotein subunit 2, mitochondrial [Precursor]
Synonyms EC 1.3.5.1
Flavoprotein subunit 2 of complex II
FP
Gene name
Name: SDH1-2
OrderedLocusNames: At2g18450
ORFNames: T30D6.4
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/45471; PubMed=10617197 [NCBI, ExPASy, EBI, Israel, Japan]
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
Nature 402:761-768(1999).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
DOI=10.1126/science.1071006; PubMed=11910074 [NCBI, ExPASy, EBI, Israel, Japan]
Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T., Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y., Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K., Shinagawa A., Shinozaki K.;
"Functional annotation of a full-length Arabidopsis cDNA collection.";
Science 296:141-145(2002).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
[4]
SUBUNIT, AND TISSUE SPECIFICITY.
DOI=10.1023/A:1019926301981; PubMed=12374303 [NCBI, ExPASy, EBI, Israel, Japan]
Figueroa P., Leon G., Elorza A., Holuigue L., Araya A., Jordana X.;
"The four subunits of mitochondrial respiratory complex II are encoded by multiple nuclear genes and targeted to mitochondria in Arabidopsis thaliana.";
Plant Mol. Biol. 50:725-734(2002).
[5]
IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], AND SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
DOI=10.1105/tpc.016055; PubMed=14671022 [NCBI, ExPASy, EBI, Israel, Japan]
Heazlewood J.L., Tonti-Filippini J.S., Gout A.M., Day D.A., Whelan J., Millar A.H.;
"Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.";
Plant Cell 16:241-256(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AC006439; AAD15493.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AK119142; BAC43712.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BT005938; AAO64873.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR D84564; D84564.
RefSeq NP_179435.1; -.
UniGene At.39995
3D structure databases
HSSP P10444; 1NEK. [HSSP ENTRY / PDB]
SMR Q9ZPX5; 39-632.
ModBase Q9ZPX5.
Organism-specific databases
GeneFarm 2186; 174.
TAIR At2g18450; -.
Gene expression databases
ArrayExpress Q9ZPX5; -.
GermOnline AT2G18450; Arabidopsis thaliana.
Ontologies
GO
GO:0005739; Cellular component: mitochondrion (inferred from direct assay from TAIR).
QuickGo view.
Family and domain databases
InterPro IPR003953; FAD_bind2_N.
IPR013027; FAD_pyr_nucl-diS_OxRdtase.
IPR003952; FRD_SDH_FAD_BS.
IPR004112; Fum_Rdtase/Succ_DHase_flav_C.
IPR011281; Succ_DHase_flav_su_fwd.
IPR014006; Succ_Dhase_frdA_Gneg.
Graphical view of domain structure.
Pfam PF00890; FAD_binding_2; 1.
PF02910; Succ_DH_flav_C; 1.
Pfam graphical view of domain structure.
PRINTS PR00368; FADPNR.
TIGRFAMs TIGR01816; sdhA_forward; 1.
TIGR01812; sdhA_frdA_Gneg; 1.
PROSITE PS00504; FRD_SDH_FAD_BINDING; 1.
BLOCKS Q9ZPX5.
Genome annotation databases
GeneID 816359; -.
GenomeReviews CT485783_GR; AT2G18450.
KEGG ath:AT2G18450; -.
NMPDR fig|3702.1.peg.8841; -.
Other
ProtoNet Q9ZPX5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Electron transport; FAD; Flavoprotein; Membrane; Mitochondrion; Mitochondrion inner membrane; Oxidoreductase; Transit peptide; Transport; Tricarboxylic acid cycle.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
TRANSIT   1    29  29     Mitochondrion (Potential). 
CHAIN   30   632  603     Succinate dehydrogenase [ubiquinone] flavoprotein subunit 2, mitochondrial. PRO_0000247592
NP_BIND   77    92  16     FAD (By similarity). 
ACT_SITE   327   327        Proton acceptor (By similarity). 
BINDING   283   283        Substrate (By similarity). 
BINDING   295   295        Substrate (By similarity). 
BINDING   394   394        Substrate (By similarity). 
BINDING   439   439        Substrate (By similarity). 
MOD_RES   85    85        Tele-8alpha-FAD histidine (By similarity). 
Sequence information
Length: 632 AA [This is the length of the unprocessed precursor] Molecular weight: 69363 Da [This is the MW of the unprocessed precursor] CRC64: DEC34651679CEF88 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MWRCLRVASS SRRSESNGAF ITSQLSRFFS APPSAGDKSS YTIVDHTYDA VVVGAGGAGL 

        70         80         90        100        110        120 
RAAIGLSEHG FNTACITKLF PTRSHTVAAQ GGINAALGNM SVDDWRWHMY DTVKGSDWLG 

       130        140        150        160        170        180 
DQDAIQYMCR EAPKAVIELE NYGLPFSRTE DGKIYQRAFG GQSLEFGIGG QAYRCACAAD 

       190        200        210        220        230        240 
RTGHALLHTL YGQAMKHNTQ FFVEYFALDL IMNSDGTCQG VIALNMEDGT LHRFHAGSTI 

       250        260        270        280        290        300 
LATGGYGRAY FSATSAHTCT GDGNAMVARA GLPLQDLEFV QFHPTGIYGA GCLITEGARG 

       310        320        330        340        350        360 
EGGILRNSEG EKFMDRYAPT ARDLASRDVV SRSMTMEIRQ GRGAGPMKDY LYLYLNHLPP 

       370        380        390        400        410        420 
EVLKERLPGI SETAAIFAGV DVTREPIPVL PTVHYNMGGI PTNYHGEVIT LRGDDPDAVV 

       430        440        450        460        470        480 
PGLMAAGEAA CASVHGANRL GANSLLDIVV FGRACANRVA EIQKPGEKLK PLEKDAGEKS 

       490        500        510        520        530        540 
IEWLDRIRNS NGSLPTSKIR LNMQRVMQNN AAVFRTQETL EEGCDLIDKT WDSFGDVKVT 

       550        560        570        580        590        600 
DRSMIWNSDL IETMELENLL VNACITMHSA EARKESRGAH AREDFTKRDD ANWMKHTLGY 

       610        620        630 
WEEGNVKLEY RPVHMKTLDD EVDTFPPKPR VY 

Q9ZPX5 in FASTA format

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