ExPASy Proteomics Server

Accession	MF_00232
Dates	1-JUN-2001 (Created) 25-NOV-2009 (Last updated, Version 20)

Data class

Protein

Predictors

HAMAP; MF_00232; [distribution of match scores in UniProtKB];[seed alignment for MF_00232]

Names

eIF-2-beta

Identifier

IF2B

Protein name

RecName: Full=Translation initiation factor 2 subunit beta; AltName: Full=eIF-2-beta; AltName: Full=aIF2-beta;

Gene name

eif2b

FUNCTION: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (By similarity).

SUBUNIT: Heterotrimer composed of an alpha, a beta and a gamma chain (By similarity).

SIMILARITY: Belongs to the eIF-2-beta/eIF-5 family.

SIMILARITY: Contains 1 TRAM domain.

Pfam	PF01873; eIF-5_eIF-2B; 1;
TIGRFAMs	TIGR00311; aIF-2beta; 1;
PROSITE	PS50926; TRAM; 0-1; trigger=PRU00208;

Initiation factor, Protein biosynthesis.

GO:0003743; Molecular function: translation initiation factor activity.
GO:0006413; Biological process: translational initiation.

Size range:	132-209 amino acids
Related UniRules:	None
Template:	O24473 (IF2B_WHEAT)
Scope:	Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None