ExPASy Proteomics Server

Accession	MF_01140
Dates	2-MAR-2004 (Created) 14-DEC-2009 (Last updated, Version 17)

Data class

Protein

Predictors

HAMAP; MF_01140; [distribution of match scores in UniProtKB];[seed alignment for MF_01140]

Names

LytR

Identifier

LYAT

Protein name

RecName: Full=Transcriptional regulator lytR; AltName: Full=Membrane-bound protein lytR;

Gene name

lytR

FUNCTION: Attenuator role for operon expression (By similarity).

SUBCELLULAR LOCATION: Cell membrane; Single-pass type II membrane protein (Potential).

SIMILARITY: Belongs to the lytR/cpsA/psr regulatory protein family.

Pfam	PF03816; LytR_cpsA_psr; 1;
TIGRFAMs	TIGR00350; lytR_cpsA_psr; 1;

Cell membrane, Membrane, Transmembrane, Signal-anchor, Transcription regulation, Transcription.

GO:0003700; Molecular function: transcription factor activity.
GO:0016481; Biological process: negative regulation of transcription.
GO:0005886; Cellular component: plasma membrane.

From: LYAT_BACSU (Q02115)
Key		From		To		Description		Condition		FTGroup
TOPO_DOM		Nter		11		Cytoplasmic (Potential)
TRANSMEM		12		32		Signal-anchor for type II membrane protein (Potential)
TOPO_DOM		33		Cter		Extracellular (Potential)

Size range:	303-320 amino acids
Related UniRules:	None
Template:	Q02115 (LYAT_BACSU)
Scope:	Bacteria; Bacillaceae Bacteria; Enterococcus
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	The proteins belonging to this family are unrelated to LytR from S. aureus, which is part of a two-component regulatory system that, together with LytS, is involved in autolysis and cell wall metabolism.