ExPASy Proteomics Server

Accession	MF_02010
Dates	2-MAY-2008 (Created) 17-FEB-2010 (Last updated, Version 6)

Data class

Protein

Predictors

HAMAP; MF_02010; [distribution of match scores in UniProtKB];[seed alignment for MF_02010]

Names

IraD

Identifier

IRAD

Protein name

RecName: Full=Anti-adapter protein iraD;

Gene name

iraD

FUNCTION: Inhibits rpoS proteolysis by regulating rssB activity, thereby increasing the stability of the sigma stress factor rpoS during oxidative stress. Its effect on rpoS stability is due to its interaction with rssB, which probably blocks the interaction of rssB with rpoS, and the consequent delivery of the rssB-rpoS complex to the clpXP protein degradation pathway (By similarity).

SUBUNIT: Interacts with rssB (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the GpW/Gp25 family. IraD subfamily.

Pfam	PF04965; GPW_gp25; 1;

Cytoplasm, Stress response.

GO:0033554; Biological process: cellular response to stress.
GO:0005737; Cellular component: cytoplasm.

Size range:	126-130 amino acids
Related UniRules:	None
Template:	P39375 (IRAD_ECOLI)
Scope:	Bacteria; Enterobacteriaceae
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None