This is both a tool and a database. Via a web service, users can generate i) integrated proteogenomics databases (iPtgxDBs) that can be used to identify as of yet missing protein-coding genes in prokaryotic organisms, and ii) a GFF file that contains all integrated annotations from reference genome annotations, gene prediction softwares like Prodigal, and a modified 6-frame translation (considering alternative start codons). Users are encouraged to make their iPtgxDBs available.